某些咪唑并[1,2 - a]嘧啶的合成与抗菌活性
Synthesis and antimicrobial activity of certain imidazo[1,2-a]pyrimidines.
作者信息
Revanker G R, Matthews T R, Robins R K
出版信息
J Med Chem. 1975 Dec;18(12):1253-5. doi: 10.1021/jm00246a018.
PMID:811799
Abstract
A series of 5-substituted and 5,7-disubstituted imidazo[1,2-a]pyrimidines has been prepared. The in vitro antimicrobial activity of these compounds against a variety of microorganisms is reported. 5-n-Octylaminoimidazo[1,2-a]pyrimidine exhibited significant activity against all the microorganisms studied.
摘要
已制备了一系列5-取代和5,7-二取代的咪唑并[1,2-a]嘧啶。报道了这些化合物对多种微生物的体外抗菌活性。5-正辛基氨基咪唑并[1,2-a]嘧啶对所有研究的微生物都表现出显著活性。
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