Rodríguez J, Nieto R M, Crews P
Department of Chemistry and Biochemistry, University of California, Santa Cruz 95064.
J Nat Prod. 1993 Dec;56(12):2034-40. doi: 10.1021/np50102a002.
New bengazoles 3-9 as inseparable mixtures are reported from the sponge Jaspis cf. coricea collected in Papua New Guinea. These compounds contain a new variation of the unusual bisoxazole core present in bengazole A [1]. The B-ring oxazole hexatetraol side chain is varyingly substituted with either myristic acid or 13-methylmyristic acid. Hydrolysis of three different bengazole mixtures each yielded an identical tetraol, bengazole Z [11].
据报道，从在巴布亚新几内亚采集的海绵Jaspis cf. coricea中分离出了新的苯并唑类化合物3-9，它们是不可分离的混合物。这些化合物含有苯并唑A [1]中存在的不寻常双恶唑核心的新变体。B环恶唑己糖醇侧链被肉豆蔻酸或13-甲基肉豆蔻酸不同程度地取代。三种不同的苯并唑混合物水解后均产生了相同的四醇，即苯并唑Z [11]。
