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Cytotoxic and antibacterial labdane-type diterpenes from the aerial parts of Cistus incanus subsp. creticus.

作者信息

Chinou I, Demetzos C, Harvala C, Roussakis C, Verbist J F

机构信息

Dept. of Pharmacy, Panepistimiopolis Zografou, Athens, Greece.

出版信息

Planta Med. 1994 Feb;60(1):34-6. doi: 10.1055/s-2006-959403.

DOI:10.1055/s-2006-959403
PMID:8134413
Abstract

Seven labdane-type diterpenoids were isolated from the leaves of Cistus incanus subsp. creticus; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against three cell line systems: KB, P-388; and NSCLC-N6. Their antibacterial and antifungal activities were tested against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosae, Enterobacter cloacae, Escherichia coli, Klebsiella pneumonia, Torulopsis glabrata, Saccharomyces cerevisiae, and Candida albicans as well.

摘要

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