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膳食姜黄(姜黄属植物)对大鼠肝脏中铁诱导的脂质过氧化的影响。

Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver.

作者信息

Reddy A C, Lokesh B R

机构信息

Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, India.

出版信息

Food Chem Toxicol. 1994 Mar;32(3):279-83. doi: 10.1016/0278-6915(94)90201-1.

DOI:10.1016/0278-6915(94)90201-1
PMID:8157223
Abstract

Male Wistar rats were fed a control diet or the control diet supplemented with 1% (by weight) turmeric for 10 wk. In rats injected with 30 mg Fe2+/kg body weight, lipid peroxidation was 29 and 35% lower in liver homogenates and microsomes, respectively, of turmeric-fed rats than in those of rats fed the control diet. The activities of superoxide dismutase, catalase and glutathione peroxidase were higher (by 19, 19 and 20%, respectively) in liver homogenates of rats fed the turmeric-containing diet in comparison with the controls. These studies indicate that dietary turmeric lowers lipid peroxidation by enhancing the activities of antioxidant enzymes.

摘要

将雄性Wistar大鼠分为两组,一组喂食对照饮食,另一组喂食添加了1%(重量)姜黄的对照饮食,持续10周。给大鼠注射30mg Fe2+/kg体重后,喂食姜黄的大鼠肝脏匀浆和微粒体中的脂质过氧化分别比喂食对照饮食的大鼠低29%和35%。与对照组相比,喂食含姜黄饮食的大鼠肝脏匀浆中超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶的活性更高(分别高19%、19%和20%)。这些研究表明,饮食中的姜黄通过增强抗氧化酶的活性来降低脂质过氧化。

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