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圣巴巴拉县糖尿病视网膜病变筛查可行性研究:糖尿病病程和收缩压的意义

The Santa Barbara County diabetic retinopathy screening feasibility study: significance of diabetes duration and systolic blood pressure.

作者信息

Lewis J M, Jovanovic-Peterson L, Ahmadizadeh I, Bevier W, Peterson C M, Williams B

机构信息

Sansum Medical Research Foundation, Santa Barbara Cottage Hospital, CA 93105.

出版信息

J Diabetes Complications. 1994 Jan-Mar;8(1):51-4. doi: 10.1016/1056-8727(94)90011-6.

Abstract

The objective of this study was to examine the feasibility and utility of screening for eye disease and hypertension in a group of diabetic patients. A sample of 338 outpatients in Santa Barbara County were included and had non-mydriatic retinal photography and measurement of blood pressure and visual acuity. Each patient completed a questionnaire including age, type of diabetes (type I or type II), duration of diabetes, and smoking history. Photographs were read by an internist and ophthalmologist, and grouped into one of five categories: (1) normal, (2) background retinopathy, (3) preproliferative retinopathy, (4) proliferative retinopathy, and (5) other abnormality. Patients with abnormalities were referred for treatment. Thirty-two percent of the population had retinopathy, and 16% had disease requiring urgent referral for treatment. Mean systolic blood pressure (MSBP) was found to be higher in patients with all types of retinopathy (132 mm Hg versus 124 mm Hg, p < 0.001). The relationship remained significant when smokers and nonsmokers were considered separately. No significant difference was found in MSBP between patients with severe retinopathy (preproliferative or proliferative) and those with background changes (133 mm Hg versus 131 mm Hg, respectively, p > 0.5). The other factor found to be related to retinopathy was the duration of diabetes. Type I patients with retinopathy had diabetes for 19 years versus 12 for those without (p < 0.01). Type II patients with retinopathy had diabetes for 10 years versus 6 for those without retinopathy (p < 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是检验对一组糖尿病患者进行眼病和高血压筛查的可行性及实用性。纳入了圣巴巴拉县的338名门诊患者,对其进行了免散瞳视网膜摄影、血压测量和视力检测。每位患者填写了一份问卷,内容包括年龄、糖尿病类型(I型或II型)、糖尿病病程和吸烟史。照片由一名内科医生和一名眼科医生阅片,并分为五类之一:(1)正常,(2)背景性视网膜病变,(3)增殖前期视网膜病变,(4)增殖性视网膜病变,(5)其他异常。有异常的患者被转诊接受治疗。32%的人群患有视网膜病变,16%的患者患有需要紧急转诊治疗的疾病。发现所有类型视网膜病变患者的平均收缩压(MSBP)更高(132 mmHg对124 mmHg,p<0.001)。分别考虑吸烟者和非吸烟者时,这种关系仍然显著。重度视网膜病变(增殖前期或增殖性)患者与有背景改变的患者之间的MSBP无显著差异(分别为133 mmHg对131 mmHg,p>0.5)。另一个与视网膜病变相关的因素是糖尿病病程。患有视网膜病变的I型患者糖尿病病程为19年,无视网膜病变者为12年(p<0.01)。患有视网膜病变的II型患者糖尿病病程为10年,无视网膜病变者为6年(p<0.02)。(摘要截短于250字)

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