Fletcher M A, Brown D R, Landers S, Seguin J
Newborn Service, George Washington University Medical Center, Washington, DC 20037.
Am J Perinatol. 1994 Mar;11(2):94-9. doi: 10.1055/s-2007-994564.
The Study Group for Complications of Perinatal Care through 13 of its participating neonatal intensive care units conducted an audit of umbilical artery catheter (UAC) use over 3 months. Of 1941 patient admissions, 582 (30%) had a UAC inserted and left in place for a mean of 4.9 days. The mean supplemental oxygen concentration (FIO2) at removal was 0.35 with over 55% of UACs remaining in place until FIO2 was less than 0.26. Institutional practices varied widely for positioning the catheter tip, use of heparin, and types of infusates, as did the frequency of adverse events that prompted removal of the UAC. Most institutions with multiple physicians found less consistency in practice patterns within their own units than presumed prior to the audit. Just two institutions preferred catheter placement in the abdominal aorta (low) with the others selecting a low site only after detecting a malposition below the initially sought thoracic level. All but one group routinely used heparin, although in varying concentrations and total doses. Patient weight and catheter duration were inversely correlated, with smaller patients having catheters left in place for significantly longer periods (P < 0.01). Similarly, smaller patients had a higher likelihood of catheter removal because of an adverse event; the adverse events were not necessarily related to longer duration. A significant relationship existed between positioning a catheter tip in the abdominal aorta and removal for adverse events (P < 0.05).
围产期护理并发症研究小组通过其13个参与研究的新生儿重症监护病房,对脐动脉导管(UAC)使用情况进行了为期3个月的审核。在1941例入院患者中,582例(30%)插入了UAC并留置,平均留置时间为4.9天。拔除时的平均补充氧气浓度(FIO2)为0.35,超过55%的UAC在FIO2低于0.26之前一直留置。在导管尖端定位、肝素使用、输注液类型以及促使拔除UAC的不良事件发生频率方面,各机构的做法差异很大。大多数有多名医生的机构发现,其各科室内部的实践模式一致性低于审核前的预期。只有两家机构倾向于将导管置于腹主动脉(低位),其他机构只有在检测到最初寻求的胸段水平以下位置不当后才选择低位。除一组外,所有组均常规使用肝素,尽管浓度和总剂量各不相同。患者体重与导管留置时间呈负相关,较小的患者导管留置时间明显更长(P<0.01)。同样,较小的患者因不良事件而拔除导管的可能性更高;不良事件不一定与较长的留置时间有关。导管尖端置于腹主动脉与因不良事件而拔除之间存在显著关系(P<0.05)。