氨基糖苷类抗生素的酶促修饰：一株铜绿假单胞菌分离株中的一种新型3-N-乙酰化酶
Enzymatic modification of aminoglycoside antibiotics: a new 3-N-acetylating enzyme from a Pseudomonas aeruginosa isolate.
作者信息
Biddlecome S, Haas M, Davies J, Miller G H, Rane D F, Daniels P J
出版信息
Antimicrob Agents Chemother. 1976 Jun;9(6):951-5. doi: 10.1128/AAC.9.6.951.
Abstract
A new 3-N-aminoglycoside acetyltransferase is described, which possesses a wider substrate range than any such enzyme so far discovered in clinical isolates of antibiotic-resistant bacteria.
摘要
描述了一种新的3-N-氨基糖苷乙酰转移酶，它比迄今在抗生素抗性细菌临床分离株中发现的任何此类酶具有更广泛的底物范围。
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本文引用的文献
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Gentamicin antibiotics. 4. Some condensation products of gentamicin C2 with aromatic and aliphatic aldehydes.庆大霉素类抗生素。4. 庆大霉素C2与芳香醛和脂肪醛的一些缩合产物。
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Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.铜绿假单胞菌菌株中由脱氧链霉胺部分的酶促N-乙酰化介导的庆大霉素耐药性。
Biochemistry. 1972 Feb 29;11(5):761-5. doi: 10.1021/bi00755a013.
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3-N enzymatic acetylation of gentamicin, tobramycin, and kanamycin by Escherichia coli carrying an R factor.携带R因子的大肠杆菌对庆大霉素、妥布霉素和卡那霉素的3-N酶促乙酰化作用
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Letter: Gentamicin acetyltransferase in Escherichia coli carrying R factor.信函：携带R因子的大肠杆菌中的庆大霉素乙酰转移酶
J Antibiot (Tokyo). 1973 Oct;26(10):612-4. doi: 10.7164/antibiotics.26.612.
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J Antibiot (Tokyo). 1975 Jan;28(1):42-7. doi: 10.7164/antibiotics.28.42.
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Purification and properties of gentamicin acetyltransferase I.庆大霉素乙酰转移酶I的纯化及性质
Biochemistry. 1976 Jan 13;15(1):125-31. doi: 10.1021/bi00646a019.
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