Pitkin A D, Roberts C M, Wedzicha J A
Department of Thoracic Medicine, London Chest Hospital.
Thorax. 1994 Apr;49(4):364-6. doi: 10.1136/thx.49.4.364.
Techniques for sampling arterialised capillary blood from the finger pulp and the earlobe were first described over two decades ago but, although close agreement between arterial values and earlobe samples has been demonstrated in normal subjects, this technique is not in common usage.
Forty patients with chronic lung disease and a wide range of arterial blood gas values were studied. Simultaneous earlobe and arterial samples were drawn with the patient at rest and analysed in the same blood gas analyser. The respiratory function laboratory staff in 50 UK hospitals with a respiratory department were telephoned and asked whether the technique was used in their hospital and the reasons, if known, for not adopting it.
Earlobe and arterial blood gas tensions agreed closely over a wide range of values of arterial pH, PCO2 (mean difference 0.21, 95% confidence intervals -0.24 to +0.67 kPa) and PO2 (mean difference -0.17, 95% confidence intervals -1.09 to +0.75 kPa), especially at arterial PO2 values lower than 8 kPa. Of 50 UK centres surveyed 18% used the arterialised earlobe technique and 4% had plans to introduce it. Reasons for not using it were lack of knowledge in 64%, no blood gas analyser in 6%, the technique was considered inaccurate in 4%, and insufficient staff in 4%.
Although earlobe blood gas analysis is sufficiently accurate to be reliably substituted for arterial sampling in routine clinical practice, most centres in the UK do not use the technique. The main reasons for this appear to be lack of knowledge of its existence and uncertainty over its accuracy.
从指腹和耳垂采集动脉化毛细血管血的技术早在二十多年前就已被描述,但尽管在正常受试者中已证明动脉值与耳垂样本之间具有高度一致性,但该技术并未得到广泛应用。
对40例患有慢性肺部疾病且动脉血气值范围广泛的患者进行了研究。让患者在静息状态下同时采集耳垂和动脉样本,并在同一台血气分析仪上进行分析。研究人员致电英国50家设有呼吸科的医院的呼吸功能实验室工作人员,询问他们所在医院是否使用该技术,以及若已知未采用该技术的原因。
在动脉pH、PCO2(平均差值0.21,95%置信区间-0.24至+0.67 kPa)和PO2(平均差值-0.17,95%置信区间-1.09至+0.75 kPa)的广泛取值范围内,耳垂和动脉血气张力高度一致,尤其是在动脉PO2值低于8 kPa时。在接受调查的50个英国中心中,18%使用动脉化耳垂技术,4%计划引入该技术。不使用该技术的原因包括:64%的人缺乏相关知识,6%的人没有血气分析仪,4%的人认为该技术不准确,4%的人认为工作人员不足。
尽管耳垂血气分析足够准确,可在常规临床实践中可靠地替代动脉采样,但英国大多数中心并未使用该技术。其主要原因似乎是对该技术的存在缺乏了解以及对其准确性存在疑虑。