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Cellular immunity to Bacteroides fragilis capsular polysaccharide.对脆弱拟杆菌荚膜多糖的细胞免疫
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Interleukin-1 production by antibiotic-treated human monocytes.抗生素处理的人单核细胞产生白细胞介素-1
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Aryl-fluoroquinolone derivatives A-56619 (difloxacin) and A-56620 inhibit mitogen-induced human mononuclear cell proliferation.芳基氟喹诺酮衍生物A-56619（二氟沙星）和A-56620可抑制丝裂原诱导的人单核细胞增殖。
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Use of lymphokines in treatment of experimental intra-abdominal abscess caused by Bacteroides fragilis.淋巴因子在治疗脆弱拟杆菌引起的实验性腹腔内脓肿中的应用。
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芦氟沙星和环丙沙星对感染脆弱拟杆菌小鼠T细胞亚群及肿瘤坏死因子产生的体内效应

In vivo effects of rufloxacin and ciprofloxacin on T-cell subsets and tumor necrosis factor production in mice infected with Bacteroides fragilis.

作者信息

Gollapudi S V, Chuah S K, Harvey T, Thadepalli H D, Thadepalli H

机构信息

Department of Internal Medicine, Charles R. Drew University of Medicine and Science, UCLA School of Medicine 90059.

出版信息

Antimicrob Agents Chemother. 1993 Aug;37(8):1711-2. doi: 10.1128/AAC.37.8.1711.

DOI:10.1128/AAC.37.8.1711
PMID:8215290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC188049/
Abstract

We investigated the in vivo effects of rufloxacin and ciprofloxacin on T-cell subsets and tumor necrosis factor production in mice infected with Bacteroides fragilis. These quinolones did not alter the helper/suppressor ratio but did modulate the kinetics of tumor necrosis factor production in infected animals. This result correlated with the observed therapeutic efficacies of the quinolones.

摘要

我们研究了芦氟沙星和环丙沙星对感染脆弱拟杆菌的小鼠体内T细胞亚群及肿瘤坏死因子产生的影响。这些喹诺酮类药物未改变辅助/抑制细胞比例，但确实调节了感染动物体内肿瘤坏死因子产生的动力学。这一结果与观察到的喹诺酮类药物的治疗效果相关。