Schwartz B S, Goldstein M D, Childs J E
Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Md.
Am J Public Health. 1993 Dec;83(12):1746-8. doi: 10.2105/ajph.83.12.1746.
In 1990, a second cross-sectional study of outdoor workers (n = 758) at high risk for Lyme disease was conducted. A questionnaire was administered, and antibodies to Borrelia burgdorferi and tick salivary gland proteins (antitick saliva antibody, a biologic marker of tick exposure) were assayed by enzyme-linked immunosorbent assay. The statewide Lyme disease seroprevalence increased from 8.1% in 1988 to 18.7% in 1990. Antitick saliva antibody seropositivity varied by county and was associated with measures of self-reported tick exposure. The data suggested that the prevalence of B. burgdorferi infection increased in New Jersey outdoor workers from 1988 to 1990.
1990年，针对莱姆病高风险户外工作者开展了第二项横断面研究（n = 758）。研究人员发放了问卷，并通过酶联免疫吸附测定法检测了抗伯氏疏螺旋体抗体和蜱唾液腺蛋白抗体（抗蜱唾液抗体，蜱暴露的生物学标志物）。全州范围内的莱姆病血清阳性率从1988年的8.1%升至1990年的18.7%。抗蜱唾液抗体血清阳性率因县而异，且与自我报告的蜱暴露指标相关。数据表明，1988年至1990年期间，新泽西州户外工作者中伯氏疏螺旋体感染率有所上升。
