“无反应性”肺结核患者淋巴组织中抗原特异性淋巴细胞滞留的初步证据。
Preliminary evidence for the trapping of antigen-specific lymphocytes in the lymphoid tissue of 'anergic' tuberculosis patients.
作者信息
Rook G A, Carswell J W, Stanford J L
出版信息
Clin Exp Immunol. 1976 Oct;26(1):129-32.
Abstract
Lymphocyte-transformation responses to mycobacterial antigens have been studied, using paired blood and lymph node samples from 'normal' Ugandans, (hernia repairs or orthopaedic cases) or from patients with tuberculosis, Mycobacterium ulcerans infection, or injection abscesses. The results suggest that in some individuals, antigen reactive cells, although absent from the periphery, may be demonstrable in the lymph nodes. This phenomenon is most striking in skin-test negative tuberculosis patients.
摘要
已利用来自“正常”乌干达人（疝气修补或骨科病例）、结核病患者、溃疡分枝杆菌感染患者或注射脓肿患者的配对血液和淋巴结样本，研究了对分枝杆菌抗原的淋巴细胞转化反应。结果表明，在一些个体中，抗原反应性细胞虽然在外周血中不存在，但在淋巴结中可能可以检测到。这种现象在皮肤试验阴性的结核病患者中最为明显。
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