Florack E I, Zielhuis G A, Pellegrino J E, Rolland R
Department of Epidemiology, University of Nijmegen, The Netherlands.
Int J Epidemiol. 1993 Oct;22(5):878-84. doi: 10.1093/ije/22.5.878.
The influence of occupational physical activity on early pregnancy failure was examined in a population of 24 cleaners, 36 kitchen staff and 110 clerical workers from 39 Dutch hospitals who were enrolled before becoming pregnant between August 1987 and January 1989. The occupational energy expenditure was defined by an intensity and a fatigue score, which were studied alone and in combination with working hours and working speed. The occupational biomechanic load was defined by a peak and a chronic pressure score. The intensity and the fatigue score of the work, whether or not in combination with working hours and working speed, were not related to the occurrence of spontaneous abortion. Work involving a high biomechanic load, in particular high peak pressure scores, showed an odds ratio (OR) for spontaneous abortion of 3.1 (95% confidence interval [CI]: 1.1-8.9). There were strong indications that work involving bending (OR = 3.2; 95% CI: 1.3-9.8) rather than lifting (OR = 1.1; 95% CI: 0.3-3.4) was the main cause.
在1987年8月至1989年1月期间，对荷兰39家医院的24名清洁工、36名厨房工作人员和110名文职人员进行了研究，以探讨职业体力活动对早期妊娠失败的影响。这些人员在怀孕前就已登记入组。职业能量消耗由强度和疲劳评分来定义，分别对其进行研究，并与工作时间和工作速度相结合进行研究。职业生物力学负荷由峰值压力评分和慢性压力评分来定义。工作的强度和疲劳评分，无论是否与工作时间和工作速度相结合，均与自然流产的发生无关。涉及高生物力学负荷的工作，尤其是高峰值压力评分的工作，自然流产的优势比（OR）为3.1（95%置信区间[CI]：1.1 - 8.9）。有强烈迹象表明，导致自然流产的主要原因是涉及弯腰的工作（OR = 3.2；95% CI：1.3 - 9.8），而非搬运工作（OR = 1.1；95% CI：0.3 - 3.4）。
