旧大陆白蛉热流行病学的血清学研究。
Serological studies on the epidemiology of sandfly fever in the Old World.
作者信息
Tesh R B, Saidi S, Gajdamovic S J, Rodhain F, Vesenjak-Hirjan J
出版信息
Bull World Health Organ. 1976;54(6):663-74.
Abstract
Selected human sera from 59 different localities in Africa, the Mediterranean littoral, eastern Europe and Asia were examined by plaque reduction neutralization test against eight sandfly (Phlebotomus) fever virus serotypes (Sicilian, Naples, Arumowot, SudAn 754-61, Karimabad, Salehabad, Gordil and Saint Floris) known to occur in the Old World. Results of these studies provide new information on the geographic distribution and prevalence of human infection with each of the viruses. Specific neutralizing antibodies were detected against all of the agents except Salehabad. Naples and Sicilian antibodies were encountered most frequently and had the widest geographic range; moreover they were found only in areas where Phlebotomus papatasi occurs. Age-specific antibody rates for several of the viruses are presented. These data and the epidemiology of sandfly fever are discussed.
摘要
对来自非洲、地中海沿岸、东欧和亚洲59个不同地区的人血清样本进行了检测，采用蚀斑减少中和试验，针对已知在旧世界出现的8种白蛉热病毒血清型（西西里型、那不勒斯型、阿鲁莫沃特型、苏丹754 - 61型、卡里马巴德型、萨勒哈巴德型、戈尔迪尔型和圣弗洛里斯型）。这些研究结果提供了关于每种病毒在地理分布和人类感染流行情况的新信息。除萨勒哈巴德型外，针对所有病毒均检测到了特异性中和抗体。那不勒斯型和西西里型抗体最为常见，地理分布范围最广；此外，它们仅在有巴氏白蛉分布的地区被发现。还给出了几种病毒的年龄特异性抗体率。对这些数据以及白蛉热的流行病学进行了讨论。
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