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老年人群血压的季节性变化及其与环境温度的关系。

Seasonal variation of blood pressure and its relationship to ambient temperature in an elderly population.

作者信息

Woodhouse P R, Khaw K T, Plummer M

机构信息

Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, UK.

出版信息

J Hypertens. 1993 Nov;11(11):1267-74.

PMID:8301109
Abstract

OBJECTIVE

To measure the magnitude and timing of seasonal variation of blood pressure and related factors in the elderly living in the community, and to assess their potential impact on cardiovascular risk.

DESIGN

Prospective study; from January 1991 to February 1992 blood pressure and other variables were measured at 2-monthly intervals in each subject in their own homes.

SUBJECTS

Ninety-six men and women, age range 65-74 years, recruited from a single group general practice in Cambridge.

MAIN OUTCOME MEASURES

Seasonal variation of blood pressure, seasonal variation of prevalence of hypertension, seasonal variation of ambient temperature and body mass index.

RESULTS

Both systolic (SBP) and diastolic blood pressure (DBP) were greatest during the winter across the whole distribution of blood pressure. There was a fourfold increase in the proportion of subjects with blood pressures > 160/90 mmHg in winter compared with in summer. Regression analysis revealed highly significant seasonal differences in both SBP and DBP. After adjustment for confounding seasonal effects, a 1 degree C decrease in living-room temperature was associated with rises of 1.3 mmHg in SBP and 0.6 mmHg in DBP.

CONCLUSIONS

Seasonal variation of blood pressure is heightened in older adults and may partly explain the greater cardiovascular disease mortality of elderly subjects during the winter. The blood pressures of elderly people may be inversely related to the ambient temperature. The public health implications of these findings deserve further investigation.

摘要

目的

测量社区老年人血压及相关因素的季节性变化幅度和时间,并评估其对心血管风险的潜在影响。

设计

前瞻性研究;1991年1月至1992年2月,每隔两个月在每位受试者家中测量血压及其他变量。

研究对象

从剑桥的一个单一团体全科诊所招募的96名男性和女性,年龄在65 - 74岁之间。

主要观察指标

血压的季节性变化、高血压患病率的季节性变化、环境温度和体重指数的季节性变化。

结果

在整个血压分布范围内,收缩压(SBP)和舒张压(DBP)在冬季最高。与夏季相比,冬季血压>160/90 mmHg的受试者比例增加了四倍。回归分析显示SBP和DBP均存在高度显著的季节性差异。在调整混杂的季节效应后,客厅温度每降低1摄氏度,SBP升高1.3 mmHg,DBP升高0.6 mmHg。

结论

老年人血压的季节性变化更为明显,这可能部分解释了老年受试者冬季心血管疾病死亡率较高的原因。老年人的血压可能与环境温度呈负相关。这些发现对公共卫生的影响值得进一步研究。

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