Hooisma J, Hänninen H, Emmen H H, Kulig B M
Department of Neurotoxicology and Applied Neuroscience, TNO Medical Biological Laboratory, Rijswijk, The Netherlands.
Neurotoxicol Teratol. 1993 Nov-Dec;15(6):397-406. doi: 10.1016/0892-0362(93)90057-u.
The report describes the results of a cross-sectional study of solvent-exposed young and older Dutch painters and two age-matched control groups. Both traditional and computerized neurobehavioral tests were applied. The study did not detect any major differences between the two groups of painters and their two age-matched control groups. It is argued that this absence of differences is probably not due to a lack of sensitivity of the tests applied or the size of the groups studied. The level of exposure was estimated to be within a range at which previous authors have reported solvent-induced CNS effects.
该报告描述了一项针对接触溶剂的荷兰年轻和年长画家以及两个年龄匹配对照组的横断面研究结果。同时应用了传统和计算机化神经行为测试。该研究未发现两组画家及其两个年龄匹配对照组之间存在任何重大差异。有人认为,这种差异的不存在可能并非由于所应用测试的敏感性不足或所研究组的规模问题。据估计,接触水平处于先前作者报告过的溶剂诱导中枢神经系统效应的范围内。