Herz G, Gfeller J
Chemotherapy. 1977;23(1):50-7. doi: 10.1159/000221971.
The authors discuss the problem of the diagnosis of sinusitis in children from the viewpoint of the practising paediatrician, on the basis of 106 children and adolescents aged between 6 and 17 years, and suffering from sinusitis. Maxillary sinusitis (56.5%) and a combination of maxillary and ethmoidal sinusitis (24.5%) were commonest, and pan-sinusitis occurred in about 10% of cases. The commonest complaints in the history were cough, headache, pyrexia and rhinitis. The commonest clinical findings were pharyngitis, retropharyngeal drip, tenderness to pressure over the sinus points, otitis media, a deterioration in the general condition, enlarged tender angular lymph nodes, bronchitis and rhinitis. The result of treatment of sinusitis in childhood with the antibiotic used here, doxycycline, are assessed. A successful result was obtained in 94.3% of cases; cure in 77 patients (72.6%) and marked improvement in 23 (21.7%). There were six failures (5.7%). In the majority of children - 72 cases (68%), the duration of treatment was 15-21 days. It was 10-14 days in 18 children (17%) and more than 3 weeks in 16 children (15%). Rapid subjective improvement was seen in 65 cases (61.3%), and rapid objective improvement in 80 (75.5%). The tolerance of doxycycline was very good in nearly all patients. Mild symptoms of gastrointestinal intolerance were seen in two cases.
作者基于106名6至17岁患鼻窦炎的儿童和青少年,从执业儿科医生的角度探讨了儿童鼻窦炎的诊断问题。上颌窦炎(56.5%)以及上颌窦和筛窦合并炎症(24.5%)最为常见,全鼻窦炎约占病例的10%。病史中最常见的主诉是咳嗽、头痛、发热和鼻炎。最常见的临床体征是咽炎、咽后壁黏液附着、鼻窦区压痛、中耳炎、全身状况恶化、颌下淋巴结肿大压痛、支气管炎和鼻炎。评估了此处使用的抗生素多西环素治疗儿童鼻窦炎的效果。94.3%的病例取得了成功结果;77例(72.6%)治愈,23例(21.7%)明显好转。有6例失败(5.7%)。大多数儿童——72例(68%)的治疗持续时间为15至21天。18例儿童(17%)为10至14天,16例儿童(15%)超过3周。65例(61.3%)主观症状迅速改善,80例(75.5%)客观症状迅速改善。几乎所有患者对多西环素的耐受性都非常好。有2例出现轻微的胃肠道不耐受症状。