Vesterager L, Petersen K P, Nielsen R, Niordson A M, Gammeltoft M, Graudal C, Stahl D
Private Dermatological Clinics in Lyngby, Denmark.
Dermatology. 1994;188(1):32-5. doi: 10.1159/000247082.
The analgesic effect of topical application of EMLA cream for the curettage verrucae vulgaris was compared to local infiltration with lignocaine in 89 patients. The main purpose of this randomized study was to evaluate the patients' overall impression of the treatment. All patients anaesthetized by lignocaine infiltration reported it as 'an acceptable procedure' compared to only 71% of the patients treated with EMLA. It cannot be recommended to use EMLA cream as local anaesthetic for curettage of verrucae vulgaris, presumably because the highly keratotic nature of the common warts does not allow sufficient penetration of epicutaneously applied EMLA.
将89例寻常疣刮除患者外用EMLA乳膏的镇痛效果与利多卡因局部浸润的镇痛效果进行了比较。这项随机研究的主要目的是评估患者对治疗的总体印象。与仅71%接受EMLA治疗的患者相比，所有接受利多卡因浸润麻醉的患者均表示该治疗“可接受”。不推荐将EMLA乳膏用作寻常疣刮除的局部麻醉剂，可能是因为寻常疣高度角化的性质不允许经皮应用的EMLA充分渗透。
