Blossey H, Commenges D, Olson J M
Department of Statistics, University of Washington, Seattle 98195.
Genet Epidemiol. 1993;10(6):377-82. doi: 10.1002/gepi.1370100608.
Four relative-pair methods for detecting genetic linkage were applied to familial Alzheimer's disease data. Results obtained using an extended Haseman-Elston test and a weighted rank pairwise correlation test, which both use information from all relative pairs, were consistent with previously published likelihood results and appear to be more powerful than affected sib pair methods.
四种用于检测基因连锁的相对对方法被应用于家族性阿尔茨海默病数据。使用扩展的哈斯曼-埃尔斯顿检验和加权秩成对相关检验（这两种方法都使用了所有相对对的信息）得到的结果与之前发表的似然性结果一致，并且似乎比患病同胞对方法更具效力。
