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基于Hepatest的微量血凝抑制(HAI)技术的开发与应用,用于检测和定量献血者血液中的乙型肝炎表面抗体(抗-HBs)。

Development and use of a micro haemagglutination inhibition (HAI) technique, based on Hepatest, for the detection and quantitation of hepatitis B surface antibody (Anti-HBs) in blood donors.

作者信息

Wiseman I C

出版信息

J Clin Pathol. 1977 Jan;30(1):50-3. doi: 10.1136/jcp.30.1.50.

DOI:10.1136/jcp.30.1.50
PMID:838871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476638/
Abstract

A simple micro haemagglutination inhibition technique, based on Hepatest (Wellcome Reagents Limited), is described. Its application in the screening of blood donors is shown, and its sensitivity is discussed in two forms of usage and also when compared to the previous immunoelectroosmophoresis technique used in this centre.

摘要

本文描述了一种基于Hepatest(威康试剂有限公司)的简单微量血凝抑制技术。展示了其在献血者筛查中的应用,并从两种使用形式以及与该中心之前使用的免疫电渗技术相比较的角度,讨论了其敏感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2498/476638/7727a55bd959/jclinpath00159-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2498/476638/a3fe9a55c729/jclinpath00159-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2498/476638/7727a55bd959/jclinpath00159-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2498/476638/a3fe9a55c729/jclinpath00159-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2498/476638/7727a55bd959/jclinpath00159-0063-a.jpg

相似文献

1
Development and use of a micro haemagglutination inhibition (HAI) technique, based on Hepatest, for the detection and quantitation of hepatitis B surface antibody (Anti-HBs) in blood donors.基于Hepatest的微量血凝抑制(HAI)技术的开发与应用,用于检测和定量献血者血液中的乙型肝炎表面抗体(抗-HBs)。
J Clin Pathol. 1977 Jan;30(1):50-3. doi: 10.1136/jcp.30.1.50.
2
Screening of HBs antigen and detection of corresponding antibodies on groupamatic equipment.在全自动设备上筛查乙肝表面抗原并检测相应抗体。
Vox Sang. 1977 Sep;33(3):175-86. doi: 10.1111/j.1423-0410.1977.tb02250.x.
3
Screening tests for hepatitis B antigen and antibody in two colleges of education and studies on the relationship between nonspecific positive antibody tests and EB virus infection.两所教育学院的乙型肝炎抗原和抗体筛查试验以及非特异性抗体阳性试验与EB病毒感染之间的关系研究
J Clin Pathol. 1976 Oct;29(10):880-3. doi: 10.1136/jcp.29.10.880.
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A sensitive single reverse passive haemagglutination test for detecting both HBsAg and anti-HBs.一种用于检测乙肝表面抗原(HBsAg)和乙肝表面抗体(抗-HBs)的灵敏的单向被动血凝试验。
J Clin Pathol. 1979 Nov;32(11):1180-3. doi: 10.1136/jcp.32.11.1180.
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Hepatitis B surface antigen and antibody in asymptomatic blood donors.无症状献血者中的乙肝表面抗原和抗体
JAMA. 1976 Mar 8;235(10):1014-7.
6
Prevalence of hepatitis-B surface antigen by rapid passive haemagglutination inhibition technique.采用快速被动血凝抑制技术检测乙型肝炎表面抗原的患病率。
Indian J Med Res. 1979 Jun;69:978-80.
7
Detection of hepatitis B surface antigen among Scottish blood donors: evaluation of sensitive tanned-cell haemagglutination-inhibition test.苏格兰献血者中乙型肝炎表面抗原的检测:敏感鞣酸细胞血凝抑制试验的评估
Br Med J. 1975 May 24;2(5968):409-11. doi: 10.1136/bmj.2.5968.409.
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Determination of antibody to hepatitis B core antigen by means of immune adherence hemagglutination.采用免疫粘连血凝法测定乙型肝炎核心抗原抗体。
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[HBsAg in the prevention of post-transfusion hepatitis. General notes and data on the incidence in Umbria].[乙肝表面抗原在预防输血后肝炎中的作用。翁布里亚地区发病率的一般说明与数据]
Minerva Med. 1977 Nov 24;68(57):3833-7.
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Detection, by three techniques, of hepatitis B surface antigen (HBsAg) and determination of HBsAg and anti-HBs titres in patients with chronic liver disease.采用三种技术检测慢性肝病患者的乙型肝炎表面抗原(HBsAg)并测定HBsAg和抗-HBs滴度。
Gut. 1977 Jan;18(1):1-6. doi: 10.1136/gut.18.1.1.

引用本文的文献

1
Preparation and use of erythrocyte-globulin conjugates to Lassa virus in reversed passive hemagglutination and inhibition.用于拉沙病毒的红细胞-球蛋白结合物在反向被动血凝及抑制试验中的制备与应用
J Clin Microbiol. 1980 Jun;11(6):593-9. doi: 10.1128/jcm.11.6.593-599.1980.

本文引用的文献

1
A tanned cell haemagglutination test for the detection of hepatitis-associated-antigen (Au-Ag) and antibody (anti-Au).用于检测肝炎相关抗原(澳抗-Ag)和抗体(抗澳抗)的鞣酸细胞血凝试验。
Br J Haematol. 1973 Nov;25(5):619-29. doi: 10.1111/j.1365-2141.1973.tb01775.x.
2
Letter: Effectiveness of hepatitis-B immune globulin in haemodialysis patients.信件:乙肝免疫球蛋白在血液透析患者中的有效性。
Lancet. 1974 Dec 21;2(7895):1512-3. doi: 10.1016/s0140-6736(74)90249-9.
3
Risk of transfusing blood containing antibody to hepatitis-B surface antigen.
输注含有乙型肝炎表面抗原抗体血液的风险。
Lancet. 1974 Jul 27;2(7874):190-3. doi: 10.1016/s0140-6736(74)91485-8.
4
A modification of Hepatest, using the Terasaki plate, for the detection of HBSAg in blood donors.一种使用特拉萨基板对Hepatest进行改良的方法,用于检测献血者的乙肝表面抗原。
J Clin Pathol. 1976 Mar;29(3):264-6. doi: 10.1136/jcp.29.3.264.
5
Hepatitis B immune globulin--prevention of hepatitis from accidental exposure among medical personnel.乙肝免疫球蛋白——预防医务人员意外接触所致的肝炎
N Engl J Med. 1975 Nov 20;293(21):1067-70. doi: 10.1056/NEJM197511202932104.
6
An immune hemagglutination procedure with very high sensitivity applied to the detection of hepatitis B antibody and antigen and immune complex.一种具有极高灵敏度的免疫血凝程序,应用于检测乙型肝炎抗体、抗原及免疫复合物。
Vox Sang. 1975;29(3):157-76. doi: 10.1111/j.1423-0410.1975.tb00491.x.
7
Editorial: Hepatitis B immune globulin: Evaluation of clinical trials and rationale for usage.社论:乙型肝炎免疫球蛋白:临床试验评估及使用原理
N Engl J Med. 1975 Nov 20;293(21):1093-4. doi: 10.1056/NEJM197511202932109.
8
Hepatitis B "immune" globulin: effectiveness in prevention of dialysis-associated hepatitis.乙型肝炎“免疫”球蛋白:预防透析相关肝炎的有效性
N Engl J Med. 1975 Nov 20;293(21):1063-7. doi: 10.1056/NEJM197511202932103.
9
Hepatitis B immune globulin as a prophylactic measure for spouses exposed to acute type B hepatitis.乙肝免疫球蛋白作为接触急性乙型肝炎患者的配偶的预防措施。
N Engl J Med. 1975 Nov 20;293(21):1055-9. doi: 10.1056/NEJM197511202932101.
10
Efficacy of hepatitis B immune serum globulin after accidental exposure. Preliminary report of the Veterans Administration Cooperative Study.意外暴露后乙型肝炎免疫球蛋白的疗效。退伍军人管理局合作研究的初步报告。
Lancet. 1975 Nov 15;2(7942):939-41. doi: 10.1016/s0140-6736(75)90357-8.