Donnan P T, Thomson M, Fowkes F G, Prescott R J, Housley E
Wolfson Unit for Prevention of Peripheral Vascular Diseases, Department of Public Health Sciences, University of Edinburgh, UK.
Am J Clin Nutr. 1993 Jun;57(6):917-21. doi: 10.1093/ajcn/57.6.917.
The Edinburgh Artery Study included a cross-sectional survey of 1592 men and women (aged 55-74 y). One aim was to examine relationships between an indicator of peripheral arterial disease, the ankle brachial pressure index (ABPI), and dietary factors. Nutrient intake was derived from a food-frequency questionnaire. Higher frequency of consumption of fiber-containing foods was associated with greater mean ABPI in males and higher consumption of meat and meat products were significantly associated with low mean ABPI in males and females. In a multiple linear regression with ABPI as outcome and energy-adjusted nutrients as predictors, cereal fiber (P = 0.02) and alcohol (P = 0.04) were positively associated with the ABPI in males but not in females. Dietary vitamin E(alpha-tocopherol) intake was positively associated with ABPI (P = 0.04) independently of smoking and other nutrients. Dietary vitamin C intake was significantly related to ABPI (P = 0.006) only among those who had ever smoked.
爱丁堡动脉研究对1592名男性和女性（年龄在55 - 74岁之间）进行了横断面调查。一个目的是研究外周动脉疾病指标——踝臂血压指数（ABPI）与饮食因素之间的关系。营养素摄入量来自食物频率问卷。含纤维食物的较高消费频率与男性较高的平均ABPI相关，而肉类和肉制品的较高消费与男性和女性较低的平均ABPI显著相关。在以ABPI为结果、能量调整营养素为预测因子的多元线性回归中，谷物纤维（P = 0.02）和酒精（P = 0.04）在男性中与ABPI呈正相关，但在女性中并非如此。饮食中维生素E（α - 生育酚）的摄入量与ABPI呈正相关（P = 0.04），且与吸烟及其他营养素无关。仅在曾经吸烟的人群中，饮食中维生素C的摄入量与ABPI显著相关（P = 0.006）。
