Williams G V, Rolls E T, Leonard C M, Stern C
University of Oxford, Department of Experimental Psychology, UK.
Behav Brain Res. 1993 Jun 30;55(2):243-52. doi: 10.1016/0166-4328(93)90120-f.
To analyse the functioning of the ventral striatum, the responses of more than 1,000 single neurons were recorded in a region which included the nucleus accumbens and olfactory tubercle in 5 macaque monkeys. While the monkeys performed visual discrimination and related feeding tasks, the different populations of neurons found included neurons which responded to novel visual stimuli; to reinforcement-related visual stimuli such as (for different neurons) food-related stimuli, aversive stimuli, or faces; to other visual stimuli; in relation to somatosensory stimulation and movement; or to cues which signalled the start of a task. The neurons with responses to reinforcing or novel visual stimuli may reflect the inputs to the ventral striatum from the amygdala and hippocampus, and are consistent with the hypothesis that the ventral striatum provides a route for learned reinforcing and novel visual stimuli to influence behaviour.
为了分析腹侧纹状体的功能，研究人员在5只猕猴的一个包含伏隔核和嗅结节的区域记录了1000多个单个神经元的反应。在猕猴执行视觉辨别和相关进食任务时，发现的不同神经元群体包括：对新视觉刺激有反应的神经元；对强化相关视觉刺激（如对不同神经元而言的食物相关刺激、厌恶刺激或面孔）有反应的神经元；对其他视觉刺激有反应的神经元；与体感刺激和运动相关的神经元；或对标志任务开始的线索有反应的神经元。对强化或新视觉刺激有反应的神经元可能反映了杏仁核和海马体向腹侧纹状体的输入，这与腹侧纹状体为习得的强化和新视觉刺激影响行为提供了一条途径的假设相一致。
