Oguntebi B, Clark A, Wilson J
University of Florida Health Science Center, Department of Endodontics, Gainesville 32610-0436.
J Dent Res. 1993 Feb;72(2):484-9. doi: 10.1177/00220345930720020301.
The purpose of this study was to compare the responses of mechanically exposed dental pulps which had been capped with three dissimilar materials: a bioactive ceramic (Bioglass), autologous demineralized dentin matrix (DDM), and a calcium hydroxide product (Life), with Teflon discs as controls. Mechanical dental pulp exposures were made after preparation of deep buccal Class V cavities in 48 teeth in four miniature swine. The exposures were capped and the cavity preparations restored with zinc oxide-eugenol (IRM) cement. The animals were killed after 90 days, the coronal 2/3 of the teeth removed, and sections prepared for either histological or microradiographic examination. The pulpal inflammatory reactions and the degree of reparative dentin formation were assessed from demineralized serial sections. A qualitative assessment of the degree of mineralization of the reparative dentin was made from microradiographs of undecalcified sections. The observations suggest that reparative dentin formation occurs under a variety of pulp-capping materials, but the structure of the reparative dentin varies with the material and the condition of the underlying pulp.
一种生物活性陶瓷（生物玻璃）、自体脱矿牙本质基质（DDM）和一种氢氧化钙产品（Life），并用聚四氟乙烯盘作为对照。在四只小型猪的48颗牙齿上制备深颊侧V类洞后进行机械性牙髓暴露。暴露处覆盖材料，并用氧化锌丁香酚（IRM）水门汀修复洞形。90天后处死动物，去除牙齿冠部的2/3，制备切片用于组织学或显微放射学检查。从脱钙连续切片评估牙髓炎症反应和修复性牙本质形成的程度。从不脱钙切片的显微放射照片对修复性牙本质的矿化程度进行定性评估。观察结果表明，在多种盖髓材料下均可发生修复性牙本质形成，但修复性牙本质的结构因材料和下方牙髓的状况而异。
