Hayasaka S, Noda S, Setogawa T
Department of Ophthalmology, Shimane Medical University, Izumo, Japan.
Br J Ophthalmol. 1993 Jan;77(1):39-40. doi: 10.1136/bjo.77.1.39.
The ratios of D-arabinitol (a major metabolite of Candida species) to creatinine were examined in 46 sera of 40 patients with ocular inflammatory disease and in 50 age-matched normal controls (25 men and 25 women). The mean ratio in patients with endogenous Candida endophthalmitis was higher than in the normal controls. Seven samples taken from patients with Behçet's disease during an active phase showed higher values than in the controls. Fourteen patients with Behçet's disease in remission showed D-arabinitol/creatinine values within normal range. In four patients with sarcoidosis, in two patients with Vogt-Koyanagi-Harada disease, and in 16 patients with bilateral uveitis of an unknown cause, the ratios were within normal range. It is possible that D-arabinitol, or a metabolite of Candida species, may be related in part to the active phase of Behçet's disease.
对40例眼部炎症性疾病患者的46份血清以及50名年龄匹配的正常对照者（25名男性和25名女性）检测了D-阿拉伯糖醇（念珠菌属的主要代谢产物）与肌酐的比值。内源性念珠菌性眼内炎患者的平均比值高于正常对照者。7份取自白塞病活动期患者的样本显示其值高于对照者。14例缓解期白塞病患者的D-阿拉伯糖醇/肌酐值在正常范围内。4例结节病患者、2例Vogt-小柳-原田病患者以及16例病因不明的双侧葡萄膜炎患者的比值在正常范围内。D-阿拉伯糖醇或念珠菌属的一种代谢产物可能部分与白塞病的活动期有关。
