一种从少毛豆腐柴中分离得到的新型抗菌倍半萜。
A new antibacterial sesquiterpene from Premna oligotricha.
作者信息
Habtemariam S, Gray A I, Waterman P G
机构信息
Department of Pharmaceutical Science, University of Strathclyde, Glasgow, Scotland, UK.
出版信息
J Nat Prod. 1993 Jan;56(1):140-3. doi: 10.1021/np50091a022.
PMID:8450316
Abstract
A novel sesquiterpene, 7 alpha-hydroxy-6, 11-cyclofarnes-3(15)-en-2-one [1], has been isolated from the aerial parts of Premna oligotricha (Verbenaceae) using an antimicrobial bioassay-guided isolation procedure. The sesquiterpene was identified on the basis of spectroscopic data and showed weak activity against Gram-positive bacteria Bacillus pumilus, Bacillus subtilis, Staphylococcus aureus, and Streptococcus faecalis.
摘要
采用抗菌生物活性导向分离法，从少毛豆腐柴（马鞭草科）地上部分分离得到一种新型倍半萜烯，7α-羟基-6,11-环法呢-3(15)-烯-2-酮[1]。该倍半萜烯通过光谱数据鉴定，并对革兰氏阳性菌短小芽孢杆菌、枯草芽孢杆菌、金黄色葡萄球菌和粪肠球菌表现出微弱活性。
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