Snellman E, Lauharanta J, Reunanen A, Jansén C T, Jyrkinen-Pakkasvirta T, Kallio M, Luoma J, Aromaa A, Waal J
Social Insurance Institution, Helsinki, Finland.
Br J Dermatol. 1993 Feb;128(2):172-7. doi: 10.1111/j.1365-2133.1993.tb15147.x.
The effect of heliotherapy on psoriasis skin lesions and arthritis was studied in a trial comprising 4 weeks of therapy in the Canary Islands and a 6-month follow-up period. A total of 373 patients participated in the heliotherapy and 361 patients completed the follow-up period. The severity of skin lesions was evaluated using a psoriasis severity index (PSI), and that of the arthropathy by using an arthritis index (AI). During heliotherapy, the PSI decreased significantly from the initial median value of 4.5 to the final value of 0.2. A reduction in the PSI of at least 75% was achieved in 84% of the patients. Guttate psoriasis improved significantly better than plaque-type or erythrodermic psoriasis. There was no correlation between skin type and improvement. Initially, 129 patients had symptoms of arthritis. During heliotherapy, the AI decreased significantly from the initial median value of 6 to the final value of 2. The median time until starting another treatment after heliotherapy was 80 days, and the PSI had returned to its original value in 49% of the patients in 6 months. In patients with joint symptoms the AI returned to the pretreatment level within 6 months. A 4-week heliotherapy period effectively cleared psoriasis, alleviated joint symptoms, and reduced both morbidity and treatment requirement to a considerable extent in the ensuing 6-month period.
在一项研究中，观察了日光疗法对银屑病皮肤损害和关节炎的影响，该研究包括在加那利群岛进行4周的治疗以及6个月的随访期。共有373例患者接受了日光疗法，361例患者完成了随访期。使用银屑病严重程度指数（PSI）评估皮肤损害的严重程度，使用关节炎指数（AI）评估关节病的严重程度。在日光疗法期间，PSI从初始中位数4.5显著降至最终值0.2。84%的患者实现了PSI至少降低75%。点滴状银屑病的改善明显优于斑块型或红皮病型银屑病。皮肤类型与改善情况之间无相关性。最初，129例患者有关节炎症状。在日光疗法期间，AI从初始中位数6显著降至最终值2。日光疗法后开始另一种治疗的中位时间为80天，6个月内49%的患者PSI恢复到初始值。有关节症状的患者，AI在6个月内恢复到治疗前水平。为期4周的日光疗法期有效清除了银屑病，缓解了关节症状，并在随后的6个月内将发病率和治疗需求在相当程度上降低。
