Nakajima R, Nakajima Y, Ikeda K
Department of Anesthesiology and Critical Care Medicine, Hamamatsu University School of Medicine, Japan.
Br J Anaesth. 1993 Mar;70(3):273-5. doi: 10.1093/bja/70.3.273.
We have determined the minimum alveolar concentration (MAC) for sevoflurane in elderly patients (mean age 71.4 yr). MAC was found to be 1.48 (SEM 0.08)%, which is smaller than the values for children and adults. The magnitude of the change in MAC with age is similar to that for halothane and isoflurane. The calculated anesthetic ED95 for preventing 95% of patients from moving was 1.98%.
我们已经确定了老年患者(平均年龄71.4岁)七氟醚的最低肺泡有效浓度(MAC)。发现MAC为1.48(标准误0.08)%,低于儿童和成人的值。MAC随年龄的变化幅度与氟烷和异氟烷相似。预防95%的患者出现体动的计算麻醉ED95为1.98%。