Lundbäck B, Stjernberg N, Nyström L, Lundbäck K, Lindström M, Rosenhall L
Department of Lung Medicine, Central Hospital, Boden, Sweden.
Eur J Epidemiol. 1993 Mar;9(2):123-33. doi: 10.1007/BF00158781.
A questionnaire of respiratory symptoms and diseases completed by 6610 adults in 3 age cohorts (35-36 y; 50-51 y and 65-66 y) in northern Sweden was followed-up by interview and lung function testing of 1243 subjects with asthmatic or bronchitic symptoms and 263 subjects assessed from the postal questionnaire as being healthy. We report the results of this follow-up study. According to the criteria used, 292 subjects (5.1% of the original study sample) were diagnosed as having asthma. Out of the 1243 subjects 334 (5.9% of the original study population) were diagnosed as having chronic bronchitis. However, examination of the 263 subjects who were healthy according to the postal questionnaire showed that elderly smokers, in particular, under-reported bronchitic symptoms; taking this into account, the prevalence of chronic bronchitis is estimated to be of the order of 9%. Diagnostic difficulties were noted in 70 subjects (corresponding to 1.2% of the original study sample) in whom asthma or chronic bronchitis were strongly suspected. Further investigation of these subjects was considered necessary. In this cross-sectional study, FEV1 < 80% of predicted values was found in 36% of subjects diagnosed as having asthma and in 31% of those with chronic bronchitis. Among subjects with attacks of breathlessness and wheezing, diagnostic criteria often used for asthma in questionnaire studies, 70% were diagnosed as having asthma. Of those with chronic productive cough, 62% were diagnosed as having chronic bronchitis. We consider that trained nurses provide reliable data that may be used in epidemiological surveys of obstructive lung diseases.
一份由瑞典北部3个年龄组(35 - 36岁、50 - 51岁和65 - 66岁)的6610名成年人填写的呼吸道症状和疾病调查问卷,后续对1243名有哮喘或支气管炎症状的受试者以及263名根据邮寄问卷评估为健康的受试者进行了访谈和肺功能测试。我们报告了这项随访研究的结果。根据所使用的标准,292名受试者(占原始研究样本的5.1%)被诊断患有哮喘。在1243名受试者中,334名(占原始研究人群的5.9%)被诊断患有慢性支气管炎。然而,对根据邮寄问卷显示健康的263名受试者进行检查发现,尤其是老年吸烟者,支气管炎症状报告不足;考虑到这一点,慢性支气管炎的患病率估计约为9%。在70名受试者(相当于原始研究样本的1.2%)中发现了诊断困难,这些受试者被强烈怀疑患有哮喘或慢性支气管炎。认为有必要对这些受试者进行进一步调查。在这项横断面研究中,在被诊断患有哮喘的受试者中有36%以及患有慢性支气管炎的受试者中有31%的人FEV1低于预测值的80%。在问卷调查研究中常用于哮喘诊断标准的有呼吸急促和喘息发作的受试者中,7%被诊断患有哮喘。在有慢性咳痰的受试者中,62%被诊断患有慢性支气管炎。我们认为,经过培训的护士提供的可靠数据可用于阻塞性肺疾病的流行病学调查。