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中性粒细胞减少患者气管切开术的安全性:26例连续病例的回顾性研究

Safety of tracheotomy in neutropenic patients: a retrospective study of 26 consecutive cases.

作者信息

Blot F, Nitenberg G, Guiguet M, Casetta M, Antoun S, Pico J L, Leclercq B, Escudier B

机构信息

Intensive Care Unit, Institut Gustave Roussy, Villejuif, France.

出版信息

Intensive Care Med. 1995 Aug;21(8):687-90. doi: 10.1007/BF01711551.

Abstract

OBJECTIVE

To evaluate the safety of tracheotomy in neutropenic ventilated cancer patients, in terms of infectious and haemorrhagic complications.

DESIGN

Retrospective study.

SETTING

A medical-surgical intensive care unit in a Cancer-hospital.

PATIENTS AND PARTICIPANTS

26 consecutive patients undergoing a tracheotomy in neutropenic period, from 1987 to 1990.

INTERVENTIONS

Tracheotomy, performed at the bedside or in operating room.

MEASUREMENTS AND RESULTS

In all neutropenic patients undergoing a tracheotomy, the characteristics and duration of both neutropenia and mechanical ventilation have been recorded. Stomal bleeding and infection, and infectious pneumonias and alveolar haemorrhage have been carefully reviewed. Platelets were transfused in 23 of the 26 patients at the time of the procedure; no local haemorrhage was observed. Neither stomal nor pulmonary infections secondary to tracheotomy were noted. No respiratory worsening was attributable to the tracheotomy. Nineteen patients (73%) died in ICU, without direct link between tracheotomy and death.

CONCLUSIONS

These findings suggest that a tracheotomy can be safely performed in neutropenic patients requiring mechanical ventilation.

摘要

目的

从感染和出血并发症方面评估中性粒细胞减少的癌症通气患者行气管切开术的安全性。

设计

回顾性研究。

地点

一家癌症医院的内科-外科重症监护病房。

患者和参与者

1987年至1990年期间连续26例在中性粒细胞减少期行气管切开术的患者。

干预措施

在床边或手术室进行气管切开术。

测量和结果

记录了所有接受气管切开术的中性粒细胞减少患者的中性粒细胞减少和机械通气的特征及持续时间。仔细审查了切口出血和感染情况,以及感染性肺炎和肺泡出血情况。26例患者中有23例在手术时输注了血小板;未观察到局部出血。未发现气管切开术继发的切口或肺部感染。气管切开术未导致呼吸状况恶化。19例患者(73%)在重症监护病房死亡,气管切开术与死亡之间无直接关联。

结论

这些结果表明,对于需要机械通气的中性粒细胞减少患者,可安全地进行气管切开术。

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