PRINTS蛋白质指纹数据库的进展。

Progress with the PRINTS protein fingerprint database.

作者信息

Attwood T K, Beck M E, Bleasby A J, Degtyarenko K, Parry Smith D J

机构信息

Department of Biochemistry, University College London, UK.

出版信息

Nucleic Acids Res. 1996 Jan 1;24(1):182-8. doi: 10.1093/nar/24.1.182.

DOI:10.1093/nar/24.1.182

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC145564/

Abstract

PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. To date, 400 fingerprints have been constructed and stored in Prints, the size of which has doubled in the last year. The current version, 9.0, encodes approximately 2000 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbours. PRINTS thus provides a useful adjunct to the widely used PROSITE dictionary of patterns. The database is now accessible via the Database Browser on the UCL Bioinformatics server at http://www.biochem.ucl.ac.uk/bsm/dbbrowser .

摘要

PRINTS是一个源自OWL复合序列数据库的蛋白质基序“指纹”汇编。指纹是序列比对中的基序组，其保守性质使其能够用作家族成员的特征标记。迄今为止，已构建了400个指纹并存储在PRINTS中，其规模在过去一年中翻了一番。当前版本9.0编码约2000个基序，涵盖各种球状和膜蛋白、模块化多肽等。由于基序邻域提供的相互背景，指纹本质上比单基序方法具有更高的诊断可靠性。因此，PRINTS为广泛使用的PROSITE模式字典提供了有用的补充。现在可通过伦敦大学学院生物信息学服务器上的数据库浏览器（http://www.biochem.ucl.ac.uk/bsm/dbbrowser ）访问该数据库。

相似文献

1

Progress with the PRINTS protein fingerprint database.PRINTS蛋白质指纹数据库的进展。

Nucleic Acids Res. 1996 Jan 1;24(1):182-8. doi: 10.1093/nar/24.1.182.

2

Novel developments with the PRINTS protein fingerprint database.PRINTS蛋白质指纹数据库的新进展。

Nucleic Acids Res. 1997 Jan 1;25(1):212-7. doi: 10.1093/nar/25.1.212.

3

The PRINTS database of protein fingerprints: a novel information resource for computational molecular biology.蛋白质指纹图谱PRINTS数据库：计算分子生物学的新型信息资源。

J Chem Inf Comput Sci. 1997 May-Jun;37(3):417-24. doi: 10.1021/ci960468e.

4

The PRINTS protein fingerprint database in its fifth year.处于第五年的PRINTS蛋白质指纹数据库。

Nucleic Acids Res. 1998 Jan 1;26(1):304-8. doi: 10.1093/nar/26.1.304.

5

PRINTS prepares for the new millennium.PRINTS为新千年做准备。

Nucleic Acids Res. 1999 Jan 1;27(1):220-5. doi: 10.1093/nar/27.1.220.

6

PRINTS--a database of protein motif fingerprints.PRINTS——一个蛋白质基序指纹数据库。

Nucleic Acids Res. 1994 Sep;22(17):3590-6.

7

PRINTS--a protein motif fingerprint database.PRINTS——一个蛋白质基序指纹数据库。

Protein Eng. 1994 Jul;7(7):841-8. doi: 10.1093/protein/7.7.841.

8

PRINTS-S: the database formerly known as PRINTS.PRINTS-S：该数据库曾被称为PRINTS。

Nucleic Acids Res. 2000 Jan 1;28(1):225-7. doi: 10.1093/nar/28.1.225.

9

The PRINTS database: a fine-grained protein sequence annotation and analysis resource--its status in 2012.PRINTS 数据库：一种细粒度的蛋白质序列注释和分析资源——其 2012 年的状况。

Database (Oxford). 2012 Apr 15;2012:bas019. doi: 10.1093/database/bas019. Print 2012.

10

PRINTS and PRINTS-S shed light on protein ancestry.PRINTS和PRINTS-S揭示了蛋白质的起源。

Nucleic Acids Res. 2002 Jan 1;30(1):239-41. doi: 10.1093/nar/30.1.239.

引用本文的文献

1

Compilation and analysis of intein sequences.内含肽序列的汇编与分析。

Nucleic Acids Res. 1997 Mar 15;25(6):1087-93. doi: 10.1093/nar/25.6.1087.

2

The directory of P450-containing systems in 1996.1996年含细胞色素P450系统的目录。

Nucleic Acids Res. 1997 Jan 1;25(1):274-7. doi: 10.1093/nar/25.1.274.

3

The SBASE protein domain library, release 5.0: a collection of annotated protein sequence segments.SBASE蛋白质结构域文库，第5.0版：带注释的蛋白质序列片段集合。

Nucleic Acids Res. 1997 Jan 1;25(1):240-3. doi: 10.1093/nar/25.1.240.

4

Novel developments with the PRINTS protein fingerprint database.PRINTS蛋白质指纹数据库的新进展。

Nucleic Acids Res. 1997 Jan 1;25(1):212-7. doi: 10.1093/nar/25.1.212.

5

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.外排体是酿酒酵母中胞吐作用所需的一种多蛋白复合体。

EMBO J. 1996 Dec 2;15(23):6483-94.

本文引用的文献

1

Design of a discriminating fingerprint for G-protein-coupled receptors.G蛋白偶联受体鉴别指纹图谱的设计

Protein Eng. 1993 Feb;6(2):167-76. doi: 10.1093/protein/6.2.167.

2

The PIR-International databases.PIR国际数据库。

Nucleic Acids Res. 1993 Jul 1;21(13):3089-92. doi: 10.1093/nar/21.13.3089.

3

Fingerprinting G-protein-coupled receptors.G蛋白偶联受体的指纹图谱分析

Protein Eng. 1994 Feb;7(2):195-203. doi: 10.1093/protein/7.2.195.

4

Modular arrangement of proteins as inferred from analysis of homology.从同源性分析推断出的蛋白质模块化排列。

Protein Sci. 1994 Mar;3(3):482-92. doi: 10.1002/pro.5560030314.

5

PRINTS--a protein motif fingerprint database.PRINTS——一个蛋白质基序指纹数据库。

Protein Eng. 1994 Jul;7(7):841-8. doi: 10.1093/protein/7.7.841.

6

The SBASE protein domain library, release 3.0: a collection of annotated protein sequence segments.SBASE蛋白质结构域文库，第3.0版：带注释的蛋白质序列片段集合。

Nucleic Acids Res. 1994 Sep;22(17):3610-5.

7

PRINTS--a database of protein motif fingerprints.PRINTS——一个蛋白质基序指纹数据库。

Nucleic Acids Res. 1994 Sep;22(17):3590-6.

8

PROSITE: recent developments.PROSITE：最新进展。

Nucleic Acids Res. 1994 Sep;22(17):3583-9.

9

The SWISS-PROT protein sequence data bank: current status.SWISS-PROT蛋白质序列数据库：现状

Nucleic Acids Res. 1994 Sep;22(17):3578-80.

10

OWL--a non-redundant composite protein sequence database.OWL——一个非冗余复合蛋白质序列数据库。

Nucleic Acids Res. 1994 Sep;22(17):3574-7.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。