Pitarque M, Carbonell E, Lapeña N, Marsá M, Torres M, Creus A, Xamena N, Marcos R
Grup de Mutagènesi, Unitat de Genètica, Departament de Genètica i deMicrobiologia, Edifici Cn, Universitat Autònoma de Barcelona, Spain.
Mutat Res. 1996 Mar 1;367(3):161-7. doi: 10.1016/0165-1218(95)00091-7.
Service station attendants are workers that are definitely exposed to petroleum derivatives. Taking into account that this exposure has been considered to possess genotoxic risk, here we present data on the biomonitoring of a group of 50 service station workers and 43 controls. Micronuclei (MN) from peripheral blood lymphocytes has been considered as the genetic endpoint to be studied and, in addition, data on the concentration of aromatic hydrocarbons at the workplace, urinary metabolites and differential white blood cell count have also been analysed. The results obtained indicate no significant differences between petrol station attendants and controls, when the effects of petrol exposure were investigated by differential white blood cell count and analysis of MN frequencies in phytohaemagglutinin-stimulated lymphocytes. Regarding the urinary metabolites, a significant increase in the phenol level was found in the exposed workers.
加油站工作人员是肯定会接触石油衍生物的劳动者。鉴于这种接触被认为具有遗传毒性风险，在此我们展示一组50名加油站工作人员和43名对照人员的生物监测数据。外周血淋巴细胞中的微核（MN）已被视为要研究的遗传终点，此外，还分析了工作场所芳香烃浓度、尿代谢物以及白细胞分类计数的数据。当通过白细胞分类计数和对植物血凝素刺激的淋巴细胞中微核频率的分析来研究汽油暴露的影响时，所获得的结果表明加油站工作人员和对照人员之间没有显著差异。关于尿代谢物，在接触组工人中发现苯酚水平显著升高。
