在很宽的共振频率范围内肌肉水分的质子和氘核弛豫
Proton and deuteron relaxation of muscle water over wide ranges of resonance frequencies.
作者信息
Fung B M
出版信息
Biophys J. 1977 May;18(2):235-9. doi: 10.1016/S0006-3495(77)85610-5.
Abstract
The spin-lattice relaxation time (T1) of water protons in mouse muscle was studied from 10(4) to 10(8) Hz at several temperatures, and the deuteron T1 of muscle water was studied from 2.0 X 10(3) to 1.54 X 10(7) Hz at several temperatures. Proton T1's of muscle and brain water with different D2O contents were measured at 25 degrees C and 35 MHz. From the results of variable frequency and temperature measurements and the data of isotope substitution, it is concluded that the major relaxation mechanism for the protons in muscle water is the intermolecular dipolar interaction between the protons of the macromolecules and the protons of the water molecules in the hydration layer. It is also suggested that the relaxation of deuterons can be accounted for a very small fraction of water molecules directly hydrogen-bonded to the macromolecules.
摘要
在几个温度下，研究了小鼠肌肉中水质子在10⁴至10⁸赫兹范围内的自旋晶格弛豫时间（T1），并在几个温度下研究了肌肉水中氘核T1在2.0×10³至1.54×10⁷赫兹范围内的情况。在25℃和35兆赫兹下测量了不同重水含量的肌肉和脑水中的质子T1。从变频和温度测量结果以及同位素取代数据得出结论，肌肉水中质子的主要弛豫机制是大分子质子与水化层中水分子质子之间的分子间偶极相互作用。还表明，氘核的弛豫可归因于直接与大分子氢键结合的极少数水分子。
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