使用非均匀氘标记法['核磁共振窗口']研究一个21聚体RNA发夹的核磁共振结构。
The use of non-uniform deuterium labelling ['NMR-window'] to study the NMR structure of a 21mer RNA hairpin.
作者信息
Földesi A, Yamakage S I, Nilsson F P, Maltseva T V, Chattopadhyaya J
机构信息
Department of Bioorganic Chemistry, Biomedical Center, Uppsala University, Sweden.
出版信息
Nucleic Acids Res. 1996 Apr 1;24(7):1187-94. doi: 10.1093/nar/24.7.1187.
Abstract
The first synthesis of a non-uniformly deuterium labelled 21mer RNA is reported using our 'NMR-window' concept, showing its unique application in the unambiguous NMR assignment of the non-exchangeable aromatic and sugar protons.
摘要
报道了使用我们的“核磁共振窗口”概念首次合成非均匀氘标记的21聚体RNA，展示了其在不可交换芳香族和糖质子的明确核磁共振归属中的独特应用。
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