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多发性硬化症中的空肠形态学

Jejunal morphology in multiple sclerosis.

作者信息

Bateson M C, Hopwood D, MacGillivray J B

出版信息

Lancet. 1979 May 26;1(8126):1108-10. doi: 10.1016/s0140-6736(79)91790-2.

DOI:10.1016/s0140-6736(79)91790-2
PMID:86833
Abstract

In a prospective survey jejunal biopsy samples from 11 patients with multiple sclerosis on normal diets were compared with those from controls matched for age and sex. Quantitative histology, morphometry, and electron microscopy showed no difference between the two groups. Since there was no evidence that gluten sensitivity plays a role in the aetiology of multiple sclerosis, the wide adoption of gluten exclusion by patients seems unjustified.

摘要

在一项前瞻性调查中,将11名正常饮食的多发性硬化症患者的空肠活检样本与年龄和性别相匹配的对照组样本进行了比较。定量组织学、形态计量学和电子显微镜检查显示两组之间没有差异。由于没有证据表明麸质敏感性在多发性硬化症的病因学中起作用,患者广泛采用排除麸质的饮食似乎没有道理。

相似文献

1
Jejunal morphology in multiple sclerosis.多发性硬化症中的空肠形态学
Lancet. 1979 May 26;1(8126):1108-10. doi: 10.1016/s0140-6736(79)91790-2.
2
The cellular infiltrate of the jejunum in adult coeliac disease and dermatitis herpetiformis following the reintroduction of dietary gluten.成年乳糜泻和疱疹样皮炎患者重新摄入含麸质饮食后空肠的细胞浸润情况。
Gut. 1975 Sep;16(9):683-8. doi: 10.1136/gut.16.9.683.
3
Small-bowel abnormalities in multiple sclerosis.多发性硬化症中的小肠异常。
Lancet. 1976 Dec 18;2(7999):1319-22. doi: 10.1016/s0140-6736(76)91972-3.
4
Jejunal mucosal abnormalities in patients with recurrent aphthous ulceration.复发性阿弗他溃疡患者的空肠黏膜异常
Br Med J. 1976 Jan 3;1(6000):11-13. doi: 10.1136/bmj.1.6000.11.
5
Cellular infiltrate of jejunal biopsies in adult coeliac disease in relation to gluten withdrawal.成人乳糜泻空肠活检组织的细胞浸润与麸质戒断的关系
Gut. 1974 Apr;15(4):278-83.
6
Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease.接受治疗的乳糜泻患儿重新摄入含麸质饮食后空肠的细胞浸润情况。
J Clin Pathol. 1976 Jul;29(7):587-91. doi: 10.1136/jcp.29.7.587.
7
An in vitro model of gluten-sensitive enteropathy. Effect of gliadin on intestinal epithelial cells of patients with gluten-sensitive enteropathy in organ culture.麸质敏感性肠病的体外模型。麦醇溶蛋白对器官培养中麸质敏感性肠病患者肠上皮细胞的影响。
J Clin Invest. 1974 Feb;53(2):487-500. doi: 10.1172/JCI107582.
8
Evaluation of jejunal mucosa biopsy in patients with giardiasis.贾第虫病患者空肠黏膜活检的评估
Wiad Parazytol. 1984;30(3):311-9.
9
Jejunal morphology in multiple sclerosis.多发性硬化症中的空肠形态学
Lancet. 1979 Jun 16;1(8129):1300-1. doi: 10.1016/s0140-6736(79)92265-7.
10
Response of intestinal mucosa to gluten challenge in autistic subjects.自闭症患者肠道黏膜对麸质激发试验的反应。
Lancet. 1979 Oct 27;2(8148):877-8. doi: 10.1016/s0140-6736(79)92688-6.

引用本文的文献

1
Multiple sclerosis or neurological manifestations of Celiac disease.多发性硬化症或乳糜泻的神经学表现。
Adv Biomed Res. 2013 Mar 30;2:38. doi: 10.4103/2277-9175.109734. eCollection 2013.
2
A case of multiple sclerosis with atypical onset associated with autoimmune hepatitis and silent coeliac disease.一例非典型起病的多发性硬化症,伴自身免疫性肝炎及无症状性乳糜泻。
Neurol Sci. 2008 Feb;29(1):29-31. doi: 10.1007/s10072-008-0855-z. Epub 2008 Apr 1.
3
Gluten-sensitive recurrent aphthous stomatitis.麸质敏感复发性阿弗他口炎
Dig Dis Sci. 1981 Aug;26(8):737-40. doi: 10.1007/BF01316864.
4
Zinc and copper in multiple sclerosis.多发性硬化症中的锌和铜
J Neurol Neurosurg Psychiatry. 1982 Aug;45(8):691-8. doi: 10.1136/jnnp.45.8.691.