• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function.

作者信息

Willard H F

机构信息

Department of Genetics and Center for Human Genetics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

出版信息

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):6847-50. doi: 10.1073/pnas.93.14.6847.

DOI:10.1073/pnas.93.14.6847
PMID:8692907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC38895/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dff/38895/db84dded1cb0/pnas01518-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dff/38895/c947ebf703b7/pnas01518-0012-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dff/38895/db84dded1cb0/pnas01518-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dff/38895/c947ebf703b7/pnas01518-0012-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dff/38895/db84dded1cb0/pnas01518-0013-a.jpg

相似文献

1
Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function.
Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):6847-50. doi: 10.1073/pnas.93.14.6847.
2
Mammalian artificial chromosomes and chromosome transgenics.
Trends Genet. 1997 Sep;13(9):345-7. doi: 10.1016/s0168-9525(97)01256-0.
3
Centromere DNA dynamics: latent centromeres and neocentromere formation.着丝粒DNA动态变化:潜在着丝粒与新着丝粒的形成
Am J Hum Genet. 1997 Dec;61(6):1225-33. doi: 10.1086/301657.
4
Chromosome segregation and aneuploidy.
Mutagenesis. 1995 Nov;10(6):561-3. doi: 10.1093/mutage/10.6.561.
5
Construction of YAC-based mammalian artificial chromosomes.基于酵母人工染色体的哺乳动物人工染色体构建。
Nat Biotechnol. 1998 May;16(5):431-9. doi: 10.1038/nbt0598-431.
6
Kinetochore assembly and function through the cell cycle.动粒在细胞周期中的组装与功能。
Chromosoma. 2016 Sep;125(4):645-59. doi: 10.1007/s00412-016-0608-3. Epub 2016 Jul 4.
7
[The centromere of human chromosome].
Tanpakushitsu Kakusan Koso. 1993 Feb;38(3):403-11.
8
The role of CENP-B and alpha-satellite DNA: de novo assembly and epigenetic maintenance of human centromeres.着丝粒蛋白B和α-卫星DNA的作用:人类着丝粒的从头组装和表观遗传维持
Chromosome Res. 2004;12(6):543-56. doi: 10.1023/B:CHRO.0000036593.72788.99.
9
CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.着丝粒蛋白B框对于人类α卫星DNA上的从头着丝粒染色质组装是必需的。
J Cell Biol. 2002 Dec 9;159(5):765-75. doi: 10.1083/jcb.200207112. Epub 2002 Dec 2.
10
Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain.着丝粒身份由与含有CENP-A靶向结构域的组蛋白H3组装而成的核小体维持。
Mol Cell. 2007 Jan 26;25(2):309-22. doi: 10.1016/j.molcel.2006.12.018.

引用本文的文献

1
Deterministic assembly of chromosome ensembles in a programmable membrane trap array.可编程膜阱阵列中染色体组的确定性组装。
Biofabrication. 2021 Jul 20;13(4). doi: 10.1088/1758-5090/ac1258.
2
Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy.人工染色体和类微型染色体附加体在基因治疗中的应用前景。
J Biomed Biotechnol. 2010;2010. doi: 10.1155/2010/642804. Epub 2010 Aug 24.
3
Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers.

本文引用的文献

1
Going mobile: microtubule motors and chromosome segregation.走向移动:微管马达与染色体分离
Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1735-42. doi: 10.1073/pnas.93.5.1735.
2
Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage.
Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7125-30. doi: 10.1073/pnas.93.14.7125.
3
Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres.双着丝粒罗伯逊易位中着丝粒抗原的鉴定:CENP-C和CENP-E是功能性着丝粒的必要组成部分。
使用阳离子脂质和树枝状聚合物将一条60兆碱基的哺乳动物人工染色体高效体外转移至小鼠和仓鼠细胞中。
Chromosome Res. 2001;9(6):475-85. doi: 10.1023/a:1011680529073.
4
Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection.通过原核显微注射将哺乳动物人工染色体导入胚胎来生成转基因小鼠及种系传递。
Chromosome Res. 2000;8(3):183-91. doi: 10.1023/a:1009206926548.
5
Stability of a functional murine satellite DNA-based artificial chromosome across mammalian species.
Chromosome Res. 1999;7(1):3-7. doi: 10.1023/a:1009215026001.
6
Autoantibodies to components of the mitotic apparatus.针对有丝分裂器成分的自身抗体。
Mol Biol Rep. 1998 Jul;25(3):143-55. doi: 10.1023/a:1016523013819.
Hum Mol Genet. 1995 Dec;4(12):2189-97. doi: 10.1093/hmg/4.12.2189.
4
Mammalian chromosome structure.哺乳动物染色体结构。
Curr Opin Genet Dev. 1993 Jun;3(3):390-7. doi: 10.1016/0959-437x(93)90110-b.
5
The human X-inactivation centre is not required for maintenance of X-chromosome inactivation.维持X染色体失活并不需要人类X染色体失活中心。
Nature. 1994 Mar 10;368(6467):154-6. doi: 10.1038/368154a0.
6
Stringent sequence requirements for the formation of human telomeres.人类端粒形成的严格序列要求。
Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8861-5. doi: 10.1073/pnas.91.19.8861.
7
De novo formation of several features of a centromere following introduction of a Y alphoid YAC into mammalian cells.将一个Yα卫星酵母人工染色体导入哺乳动物细胞后着丝粒若干特征的从头形成。
Hum Mol Genet. 1994 May;3(5):689-95. doi: 10.1093/hmg/3.5.689.
8
The evolutionary dynamics of repetitive DNA in eukaryotes.真核生物中重复DNA的进化动力学
Nature. 1994 Sep 15;371(6494):215-20. doi: 10.1038/371215a0.
9
Dissecting the centromere of the human Y chromosome with cloned telomeric DNA.用克隆的端粒DNA剖析人类Y染色体的着丝粒。
Hum Mol Genet. 1994 Aug;3(8):1227-37. doi: 10.1093/hmg/3.8.1227.
10
A stable acentric marker chromosome: possible existence of an intercalary ancient centromere at distal 8p.一条稳定的无着丝粒标记染色体:8p远端可能存在中间型古老着丝粒。
Am J Hum Genet. 1994 Dec;55(6):1202-8.