Veien N K, Risum G, Jørgensen H P, Svejgaard A
Acta Derm Venereol. 1979;59(3):205-9.
HLA-ABC antigens were determined in 89 patients with biopsy-confirmed lichen planus, and the HLA antigen frequencies were compared with those in 1967 controls. The younger patients were predominantly male, the older patients predominantly female. No significant association was found between HLA types and lichen planus in this study. A slightly greater incidence of HLA-A3 and B5 antigens was seen, but this increased frequency was not as pronounced as reported by others. When combined, available data on HLA and lichen planus indicate a slightly, but significantly, increased frequency of HLA-A3. None of the HLA antigens known to be associated with insulin-dependent diabetes are associated with lichen planus.
对89例经活检确诊为扁平苔藓的患者进行了HLA - ABC抗原检测，并将HLA抗原频率与1967名对照者进行了比较。年轻患者以男性为主，老年患者以女性为主。本研究未发现HLA类型与扁平苔藓之间存在显著关联。观察到HLA - A3和B5抗原的发生率略有增加，但这种增加的频率不如其他人报道的那么明显。综合有关HLA和扁平苔藓的现有数据表明，HLA - A3的频率略有但显著增加。已知与胰岛素依赖型糖尿病相关的HLA抗原均与扁平苔藓无关。
