Easmon J, Heinisch G, Holzer W, Matuszczak B
Institute of Pharmaceutical Chemistry, Leopold-Franzens University, Innsbruck, Austria.
Pharmazie. 1996 Feb;51(2):76-83.
The synthesis of a variety of novel compounds structurally related to the antimicrobial natural product pyridazomycin via alkylation of appropriate azine and diazine derivatives is reported. Based on the results of preliminary antimicrobial tests the dependence of antimicrobial activity from several structural features of pyridazomycin is discussed.