Robinson S B, Ashley M, Haynes M A
Drew/Meharry/Morehouse Consortium Cancer Center, Drew University School of Medicine and Science, Los Angeles, CA 90061, USA.
J Community Health. 1996 Apr;21(2):77-87. doi: 10.1007/BF01682300.
The purpose of this study was to qualitatively assess attitudes associated with the willingness of African-Americans to participate in prostate cancer clinical trials. Fifty-six African-American males, 40 years of age and older, were recruited from South Central Los Angeles. Respondents were divided into lower or middle socio-economic groups based on education and occupation. Focus group discussions were conducted to assess their knowledge about prostate cancer and willingness to participate in prostate cancer clinical trials. In addition, information was obtained to identify their incentives and barriers towards participating in prostate cancer research. Middle socio-economic respondents expressed a greater willingness to participate in prostate cancer clinical trials than did men of lower socio-economic status. Many indicated that they would be more likely to participate if they were encouraged to do so by a physician or researcher who was viewed as being competent and compassionate. Barriers to participation in prostate cancer clinical trials included concerns about drug toxicity, medical experimentation and distrust of the medical establishment. Endeavors aimed at increasing minority representation in prostate cancer clinical studies should address these issues.
本研究的目的是定性评估非裔美国人参与前列腺癌临床试验意愿相关的态度。从洛杉矶中南部招募了56名40岁及以上的非裔美国男性。根据教育程度和职业将受访者分为社会经济地位较低或中等的群体。进行焦点小组讨论以评估他们对前列腺癌的了解以及参与前列腺癌临床试验的意愿。此外，还获取了信息以确定他们参与前列腺癌研究的动机和障碍。社会经济地位中等的受访者比社会经济地位较低的男性表示出更高的参与前列腺癌临床试验的意愿。许多人表示，如果被他们认为有能力且富有同情心的医生或研究人员鼓励，他们更有可能参与。参与前列腺癌临床试验的障碍包括对药物毒性、医学试验的担忧以及对医疗机构的不信任。旨在增加前列腺癌临床研究中少数群体代表性的努力应解决这些问题。
