Park H S, Nahm D H
Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea.
Clin Exp Allergy. 1996 Apr;26(4):423-7.
There have been very few reports of occupational allergies caused by inhalation of buckwheat flour. In this paper, we present a case of occupational asthma and rhinitis caused by buckwheat flour inhalation.
The patient had strong positive responses to grass and ragweed pollens as well. The bronchoprovocation test showed early asthmatic response to buckwheat flour extracts. Serum specific IgE antibody to buckwheat flour was detected by enzyme-linked immunosorbent assay (ELISA). In order to further identify the allergenic component of the extracts, sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and electroblotting studies were performed. Eight IgE binding components (9-55 kDa) were detected within the buckwheat flour extracts.
These results suggest that inhalation of buckwheat flour can caused IgE mediated bronchoconstriction.
吸入荞麦粉引起职业性过敏的报道极少。本文报告一例因吸入荞麦粉导致的职业性哮喘和鼻炎病例。
该患者对草花粉和豚草花粉也有强阳性反应。支气管激发试验显示对荞麦粉提取物有早期哮喘反应。采用酶联免疫吸附测定（ELISA）检测血清中针对荞麦粉的特异性IgE抗体。为进一步鉴定提取物中的过敏原成分，进行了十二烷基硫酸钠-聚丙烯酰胺凝胶电泳（SDS-PAGE）和电印迹研究。在荞麦粉提取物中检测到8种IgE结合成分（9 - 55 kDa）。
这些结果表明，吸入荞麦粉可引起IgE介导的支气管收缩。
