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多发性硬化症患者免疫球蛋白中的麻疹抗体及κ-λ轻链分布

Measles antibodies and kappa-lambda light chain distribution in immunoglobulins of patients affected with multiple sclerosis.

作者信息

Bollengier F, Mahler A

出版信息

J Neurol. 1979 Mar 22;220(2):105-12. doi: 10.1007/BF00313951.

Abstract

The presence of measles antibodies in serum immunoglobulin G fractions from seven patients affected with multiple sclerosis was investigated with HI technic. The kappa-lambda light chain ratios of all samples under investigation were evaluated. Three multiple sclerosis patients, who displayed either fractionation or a tendency towards fractionation in their serum, had slightly elevated measles antibody titers associated to increased kappa/lambda ratios.

摘要

采用血凝抑制(HI)技术研究了7例多发性硬化症患者血清免疫球蛋白G组分中麻疹抗体的存在情况。对所有受检样本的κ-λ轻链比值进行了评估。3例血清出现分离或有分离倾向的多发性硬化症患者,其麻疹抗体滴度略有升高,且κ/λ比值增加。

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