Kawashima K, Yamada S, Kobayashi H, Narita M
National Institute of Animal Health, Tsukuba, Ibaraki, Japan.
J Comp Pathol. 1996 Apr;114(3):315-23. doi: 10.1016/s0021-9975(96)80053-3.
Eleven field cases of a disease characterized by severe dyspnoea or abdominal breathing were examined post mortem. The affected pigs had antibody against porcine reproductive and respiratory syndrome virus (PRRSV). The predominant lung lesions were severe proliferative and interstitial pneumonia, and slight suppurative bronchopneumonia. The lesions were closely associated with the sites at which PRRSV and Mycoplasma hyorhinis antigens were detected. Four of five pigs inoculated with PRRSV developed slight pneumonitis. The fifth animal, which died of severe pneumonitis, yielded a heavy culture of M. hyorhinis. These findings demonstrate that dual infection with M. hyorhinis and PRRSV caused severe pulmonary lesions.
对11例以严重呼吸困难或腹式呼吸为特征的病死猪进行了尸检。患病猪具有抗猪繁殖与呼吸综合征病毒（PRRSV）的抗体。主要的肺部病变为严重的增生性间质性肺炎和轻度化脓性支气管肺炎。这些病变与检测到PRRSV和猪鼻支原体抗原的部位密切相关。接种PRRSV的5头猪中有4头发生了轻度肺炎。第五头猪死于严重肺炎，其猪鼻支原体培养物大量生长。这些发现表明，猪鼻支原体和PRRSV双重感染导致了严重的肺部病变。
