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局部冷适应诱导的低温全身冷适应

Hypothermic general cold adaptation induced by local cold acclimation.

作者信息

Savourey G, Barnavol B, Caravel J P, Feuerstein C, Bittel J H

机构信息

Unité de Thermophysiologie, La Tronche, France.

出版信息

Eur J Appl Physiol Occup Physiol. 1996;73(3-4):237-44. doi: 10.1007/BF02425482.

DOI:10.1007/BF02425482
PMID:8781852
Abstract

To study relationships between local cold adaptation of the lower limbs and general cold adaptation, eight subjects were submitted both to a cold foot test (CFT, 5 degrees C water immersion, 5 min) and to a whole-body standard cold air test (SCAT, 1 degree C, 2 h, nude at rest) before and after a local cold acclimation (LCA) of the lower limbs effected by repeated cold water immersions. The LCA induced a local cold adaptation confirmed by higher skin temperatures of the lower limbs during CFT and a hypothermic insulative general cold adaptation (decreased rectal temperature and mean skin temperature P < 0.05) without a change either in metabolic heat production or in lower limb skin temperatures during SCAT after LCA. It was concluded that local cold adaptation was related to the habituation process confirmed by decreased plasma concentrations of noradrenaline (NA) during LCA (P < 0.05). However, the hypothermic insulative general cold adaptation was unrelated either to local cold adaptation or to the habituation process, because an increased NA during SCAT after LCA (P < 0.05) was observed but was rather related to a "T3 polar syndrome" occurring during LCA.

摘要

为研究下肢局部冷适应与全身冷适应之间的关系,在通过重复冷水浸泡对下肢进行局部冷习服(LCA)之前和之后,对8名受试者进行了冷足试验(CFT,5℃水浸,5分钟)和全身标准冷空气试验(SCAT,1℃,2小时,静息时裸体)。LCA诱导了局部冷适应,这通过CFT期间下肢较高的皮肤温度得以证实,同时还诱导了一种低温绝缘性的全身冷适应(直肠温度和平均皮肤温度降低,P<0.05),LCA后在SCAT期间代谢产热或下肢皮肤温度均无变化。研究得出结论,局部冷适应与LCA期间去甲肾上腺素(NA)血浆浓度降低所证实的习服过程有关(P<0.05)。然而,低温绝缘性的全身冷适应既与局部冷适应无关,也与习服过程无关,因为在LCA后的SCAT期间观察到NA增加(P<0.05),但这更与LCA期间出现的“T3极地综合征”有关。

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