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类风湿关节炎中抗体依赖性和PHA诱导的细胞毒性

Antibody-dependent and PHA-induced cellular cytotoxicity in rheumatoid arthritis.

作者信息

Rosenberg J N, Currey H L

出版信息

Ann Rheum Dis. 1979 Aug;38(4):347-50. doi: 10.1136/ard.38.4.347.

Abstract

One hundred and thirty nine observations of antibody-dependent cell mediated cytotoxicity (ADCC) were made on 77 with rheumatoid arthritis (RA) and 17 healthy controls. There were no differences in ADCC between these 2 groups or within the RA group with regard to disease activity, duration, seropositivity, or drug treatment. Sixty observations of phytohaemagglutinin induced cytotoxicity were made on 22 patients with RA and 10 healthy controls. Again there were no differences in cytotoxicity between the 2 groups.

摘要

对77名类风湿性关节炎(RA)患者和17名健康对照者进行了139次抗体依赖性细胞介导的细胞毒性(ADCC)观察。在这两组之间或RA组内,就疾病活动度、病程、血清阳性或药物治疗而言,ADCC没有差异。对22名RA患者和10名健康对照者进行了60次植物血凝素诱导的细胞毒性观察。两组之间的细胞毒性同样没有差异。

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Lymphocyte populations in rheumatoid arthritis.
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Altered lymphocyte reactivity in rheumatoid arthritis.类风湿关节炎中淋巴细胞反应性的改变。
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Deficient lymphoid cell-mediated, PHA-induced cytotoxicity in rheumatoid arthritis patients.
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