给予乙酰乙酸对饱食泌乳大鼠乳腺葡萄糖代谢的影响。
Effects of acetoacetate administration on glucose metabolism in mammary gland of fed lactating rats.
作者信息
Robinson A M, Williamson D H
出版信息
Biochem J. 1977 Jun 15;164(3):749-52. doi: 10.1042/bj1640749.
Abstract
Administration of acetoactate to fed lactating rats rapidly decreases glucose uptake by the mammary gland, and causes an output of pyruvate, whereas lactate uptake remains unchanged. Similar changes, though not identical, occur in starved lactating rats, which suggests that the increased acetoacetate concentration in this situation may be one of the factors responsible for the alterations in glucose metabolism.
摘要
给进食的泌乳大鼠注射乙酰乙酸后，乳腺对葡萄糖的摄取迅速减少，并导致丙酮酸输出，而乳酸摄取保持不变。饥饿的泌乳大鼠也会出现类似但不完全相同的变化，这表明在这种情况下乙酰乙酸浓度的升高可能是导致葡萄糖代谢改变的因素之一。
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