老年痴呆症中神经元变化的细胞光度测定图谱
Cytophotometric mapping of neuronal changes in senile dementia.
作者信息
Mann D M, Yates P O, Barton C M
出版信息
J Neurol Neurosurg Psychiatry. 1977 Mar;40(3):299-302. doi: 10.1136/jnnp.40.3.299.
Abstract
Results of a cytophotometric study have shown a widespread reduction in cytoplasmic RNA of nerve cells. It appears, therefore, that although certain aspects of the symptomatology of senile dementia may be accounted for by lesions in particular anatomical sites, the main part of the neurological disturbance is related to more broadly based changes in nerve cell metabolism affecting much, if not all, of the CNS.
摘要
细胞光度学研究结果显示神经细胞胞质RNA普遍减少。因此，虽然老年痴呆症症状学的某些方面可能由特定解剖部位的病变所解释，但神经功能障碍的主要部分与影响中枢神经系统大部分（如果不是全部）的神经细胞代谢更广泛的变化有关。
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