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[糖皮质激素对体内可溶性及膜结合形式羧肽酶H活性的影响]

[Effect of glucocorticoids on activity of soluble and membrane-bound forms of carboxypeptidase H in vivo].

作者信息

Vernigora A N, Nikishin N N, Gengin M T

出版信息

Ukr Biokhim Zh (1978). 1995 Nov-Dec;67(6):93-7.

PMID:8867320
Abstract

Inhibition of soluble and membrane-bound carboxypeptidase H in rat hypothalamus, striatum and pituitary gland by hydrocortisone and dexamethasone treatment in vivo has been established. Differences in the dynamics of change in the activity were determined by the action of hydrocortisone and dexamethasone. Differences of the dynamics of change in soluble and membrane-bound carboxypeptidase H activity were also observed. Possible causes of these differences are discussed.

摘要

已证实，体内氢化可的松和地塞米松治疗可抑制大鼠下丘脑、纹状体和垂体中可溶性和膜结合羧肽酶H。氢化可的松和地塞米松的作用决定了活性变化动力学的差异。还观察到可溶性和膜结合羧肽酶H活性变化动力学的差异。讨论了这些差异的可能原因。

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Ukr Biokhim Zh (1978). 1995 Nov-Dec;67(6):93-7.
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