Penston J G, Pounder R E
Glaxo Wellcome, Dundee, Scotland.
Aliment Pharmacol Ther. 1996 Feb;10(1):83-9. doi: 10.1111/j.1365-2036.1996.tb00180.x.
To determine the prevalence of dyspepsia in the adult population of Great Britain and to describe the clinical features, treatment, effect of dyspepsia on daily lives and perceptions of peptic ulcer disease.
Cross-sectional survey of the adult population using structured questionnaires.
Subjects interviewed at more than 150 sampling points in England, Scotland and Wales in November 1994.
A representative sample of the adult population comprising 2112 subjects, aged 16 years or more.
The prevalence of dyspepsia in the adult population and the frequency of various characteristics in dyspeptic subjects.
The prevalence of dyspepsia was 40%. Upper abdominal pain and heartburn were the most frequently reported symptoms. Solitary symptoms were uncommon and there was frequent overlap between 'ulcer-like' and 'reflux-like' dyspepsia. Forty-six per cent of dyspeptic subjects reported moderate or severe symptoms. More than half of symptomatic subjects took medication and 22% had visited their GP during the previous year. Overall, 2% of the survey sample had been absent from work due to dyspepsia. Awareness of the factors precipitating or aggravating peptic ulcer disease was poor, particularly in relation to anti-inflammatory drugs.
The present study emphasizes the magnitude of the problem of dyspepsia in the adult population of Great Britain. The survey also shows that the public in general, and patients in particular, require more information if they are to avoid factors known to damage the upper alimentary tract.
确定英国成年人群中消化不良的患病率,并描述其临床特征、治疗情况、消化不良对日常生活的影响以及对消化性溃疡病的认知。
采用结构化问卷对成年人群进行横断面调查。
1994年11月在英格兰、苏格兰和威尔士的150多个采样点对受试者进行访谈。
2112名年龄在16岁及以上的成年人群代表性样本。
成年人群中消化不良的患病率以及消化不良受试者各种特征的发生频率。
消化不良的患病率为40%。上腹部疼痛和烧心是最常报告的症状。单一症状并不常见,“溃疡样”和“反流样”消化不良之间常有重叠。46%的消化不良受试者报告有中度或重度症状。超过一半的有症状受试者服用过药物,22%的受试者在前一年看过全科医生。总体而言,2%的调查样本因消化不良而缺勤。对促发或加重消化性溃疡病因素的认知较差,尤其是与抗炎药相关的因素。
本研究强调了英国成年人群中消化不良问题的严重性。调查还表明,公众,尤其是患者,如果要避免已知会损害上消化道的因素,需要更多信息。