Tom L W, Templeton J J, Thompson M E, Marsh R R
Division of Otolaryngology, Children's Hospital of Philadelphia, PA 19104, USA.
Int J Pediatr Otorhinolaryngol. 1996 Oct;37(2):115-20. doi: 10.1016/0165-5876(96)01388-2.
Edema contributes substantially to the postoperative discomfort and morbidity of adenotonsillectomy. In a double-blind study, 58 children undergoing adenotonsillectomy were given a single intraoperative dose of either dexamethasone or saline. The steroid markedly affected the postoperative course in the first day after surgery. According to parental reports, the percentage of patients vomiting was reduced from 48 to 4%. Severe throat pain was reported in 57% of controls and only 20% of dexamethasone patients. Twice as many steroid patients as controls tolerated some soft food on the first postoperative day. It appears that dexamethasone can greatly improve patient diet and comfort after adenotonsillectomy.
水肿在很大程度上导致了腺样体扁桃体切除术后的不适和发病情况。在一项双盲研究中，58名接受腺样体扁桃体切除术的儿童在术中接受了单剂量的地塞米松或生理盐水。这种类固醇药物对术后第一天的病程有显著影响。根据家长报告，呕吐患者的比例从48%降至4%。对照组中有57%的患者报告有严重咽痛，而地塞米松治疗组中只有20%。术后第一天，能耐受一些软食的使用类固醇药物的患者数量是对照组的两倍。看来地塞米松可以大大改善腺样体扁桃体切除术后患者的饮食和舒适度。
