将利多卡因碱化以减轻指神经阻滞的疼痛。
Alkalinisation of lignocaine to reduce the pain of digital nerve blockade.
作者信息
Cornelius P, Kendall J, Meek S, Rajan R
机构信息
Accident and Emergency Department, Bristol Royal Infirmary, United Kingdom.
出版信息
J Accid Emerg Med. 1996 Sep;13(5):339-40. doi: 10.1136/emj.13.5.339.
OBJECTIVE
To see if the alkalinisation of lignocaine caused a reduction in the pain of injection for digital nerve blockade.
METHODS
The study was a prospective randomised double blind study with each patient acting as their own control. During the study period, all patients aged 16 years and over presenting to the accident and emergency department with a condition requiring digital nerve blockade were considered for inclusion in the study. Each patient received an injection of both alkalinised and non-alkalinised lignocaine. The pain of each injection was then assessed on a visual analogue scale.
RESULTS
98 patients were entered in the study. The mean difference in pain scores between the non-alkalinised and alkalinised injections was 0.739, P < 0.001, 95% confidence interval 0.47 to 1.01.
CONCLUSIONS
Alkalinisation of lignocaine reduces the pain of injection for digital nerve blockade.
目的
观察利多卡因碱化是否能减轻指神经阻滞注射时的疼痛。
方法
本研究为前瞻性随机双盲研究，每位患者自身作为对照。在研究期间，所有16岁及以上因病情需要指神经阻滞而到急诊科就诊的患者均被纳入研究。每位患者均接受了碱化利多卡因和未碱化利多卡因的注射。然后通过视觉模拟量表评估每次注射的疼痛程度。
结果
98例患者进入研究。未碱化注射与碱化注射的疼痛评分平均差异为0.739，P<0.001，95%置信区间为0.47至1.01。
结论
利多卡因碱化可减轻指神经阻滞注射时的疼痛。
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