Mohan G, Harrison B D, Badminton R M, Mildenhall S, Wareham N J
Department of Respiratory Medicine, Norfolk and Norwich Hospital.
Br J Gen Pract. 1996 Sep;46(410):529-32.
To determine the factors contributing to death from asthma in patients aged under 65 years in East Anglia in the early 1990s.
We have performed on ongoing confidential enquiry since January 1992. For the first time a general practitioner was included in the enquiry team.
A review of the clinical and pathological data of the 50 patients reported in the first 3 years suggested that 36 of these deaths were attributable to asthma. Thirty-one patients died out of hospital (3 en route to the hospital), 2 in the Accident and Emergency department, and only 3 in hospital. Adverse social factors were found in 25 out of 34 patients, and adverse psychological characteristics in 23 of the 31 patients where these could be assessed. Only 7 appeared to have no adverse psychological or social factors. Routine medical care was considered appropriate in 20 patients, and inappropriate in 14. Twenty-four had received appropriate advice and education. Nine of the 21 patients, where this could be assessed, and half the relatives, failed to respond appropriately to worsening asthma symptoms during the fatal attack. No potentially preventable factors were identified in two women who died of end stage asthma.
This enquiry has demonstrated that inadequacies in the medical care of asthma continue to occur, although less frequently than in previous asthma-death studies. In addition, 79% of the patients had experienced psychosocial factors which appeared important in contributing to their deaths. Recommendations for identifying and managing such "at risk' patients have been circulated to all general practitioners and chest physicians in the region.
确定20世纪90年代初东安格利亚地区65岁以下哮喘患者的死亡因素。
自1992年1月以来,我们一直在进行一项保密调查。首次将一名全科医生纳入调查团队。
对前3年报告的50例患者的临床和病理数据进行回顾表明,其中36例死亡归因于哮喘。31例患者死于院外(3例在送往医院途中),2例死于急诊部,仅3例死于医院。在34例患者中有25例存在不良社会因素,在31例可评估的患者中有23例存在不良心理特征。只有7例似乎没有不良心理或社会因素。20例患者的常规医疗护理被认为是适当的,14例不适当。24例患者接受了适当的建议和教育。在21例可评估的患者中有9例以及一半的亲属在致命发作期间对哮喘症状恶化未能做出适当反应。在死于终末期哮喘的两名女性中未发现潜在可预防因素。
这项调查表明,哮喘医疗护理中的不足之处仍在发生,尽管比以往哮喘死亡研究中的频率要低。此外,79%的患者经历了心理社会因素,这些因素似乎对其死亡起到了重要作用。已向该地区所有全科医生和胸科医生分发了识别和管理此类“高危”患者的建议。