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产前超声诊断3型副流感病毒感染所致胎儿脑积水

Prenatal ultrasonographic diagnosis of fetal hydrocephalus due to infection with parainfluenza virus type 3.

作者信息

Seidman D S, Nass D, Mendelson E, Shehtman I, Mashiach S, Achiron R

机构信息

Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Ultrasound Obstet Gynecol. 1996 Jan;7(1):52-4. doi: 10.1046/j.1469-0705.1996.07010052.x.

DOI:10.1046/j.1469-0705.1996.07010052.x
PMID:8932633
Abstract

Parainfluenza virus type 3 is one of the most common causes of respiratory infection in infants. No complications of pregnancy or fetal anomalies have been reported in association with parainfluenza virus infection. A pregnancy was terminated at 22 weeks' gestation due to ultrasonographic diagnosis of hydrocephalus. Pathological examination was consistent with viral encephalitis, ventriculitis and pneumonia. Serological investigation demonstrated a significant rise in maternal antibody titers for parainfluenza virus type 3. Parainfluenza virus type 3 may be associated with severe fetal infection in the first half of pregnancy. Serological studies for this virus should be considered in cases of fetal hydrocephalus.

摘要

3型副流感病毒是婴儿呼吸道感染最常见的病因之一。尚无与3型副流感病毒感染相关的妊娠并发症或胎儿畸形的报道。因超声诊断为脑积水,一名孕妇在妊娠22周时终止妊娠。病理检查结果符合病毒性脑炎、脑室炎和肺炎。血清学调查显示,孕妇3型副流感病毒抗体滴度显著升高。3型副流感病毒可能与妊娠前半期的严重胎儿感染有关。对于胎儿脑积水病例,应考虑对该病毒进行血清学研究。

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